PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19878647-5	2010	Several key players of the unfolded protein response, including GRP78, GADD153, ATF6, XBP1 and eIF2alpha are expressed and activated in PMNs treated with ATO or other ER stress inducers.	Arsenic Trioxide	154-157	eukaryotic translation initiation factor 2A	Homo sapiens	95-104	
33946406-3	2021	Our investigations show that As2O3 treatment leads to eIF2alpha phosphorylation, upregulation of ATF4 and TRB3 expression, and an increase of EBV Zta gene expression in lymphoid tumor cell lines as well as in naturally infected epithelial cancer cell lines.	Arsenic Trioxide	29-34	eukaryotic translation initiation factor 2A	Homo sapiens	54-63	
23259068-2	2012	Here, we investigated the regulation and role of eIF2alpha in acute promyelocytic (APL) and acute myeloid leukemia (AML) cells in response to all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), the front-line therapies in APL.	Arsenic Trioxide	177-193	eukaryotic translation initiation factor 2A	Homo sapiens	49-58	
23259068-2	2012	Here, we investigated the regulation and role of eIF2alpha in acute promyelocytic (APL) and acute myeloid leukemia (AML) cells in response to all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), the front-line therapies in APL.	Arsenic Trioxide	195-198	eukaryotic translation initiation factor 2A	Homo sapiens	49-58	
23259068-3	2012	ATRA and ATO induce Ser-51 phosphorylation (inactivation) of eIF2alpha, through the induction of protein kinase C delta (PKCdelta) and PKR, but not other eIF2alpha kinases, such as GCN2 and PERK in APL (NB4) and AML cells (HL60, U937, and THP-1).	Arsenic Trioxide	9-12	eukaryotic translation initiation factor 2A	Homo sapiens	61-70	
23880367-4	2014	The results showed that As2O3 increased the expression of GRP78, CHOP, phosphorylated eIF2alpha and ATF4, all of which are the molecule of ER stress.	Arsenic Trioxide	24-29	eukaryotic translation initiation factor 2A	Homo sapiens	86-95	
19176121-8	2008	As2O3 provoked an endoplasmic reticulum (ER) stress response identified through an up regulation of EIF2A, ERN1 and ATF6 (F = 8.51, P = 0.0005).	Arsenic Trioxide	0-5	eukaryotic translation initiation factor 2A	Homo sapiens	100-105