PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2848546-1 1988 beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase III (GlcNAc-T III) catalyzes the incorporation of a "bisecting" N-acetylglucosamine (GlcNAc) residue in beta 1-4 linkage to the beta-linked mannose of the core of asparagine linked-protein bound oligosaccharides (N-glycans). n-glycans 285-294 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-75 2848546-1 1988 beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase III (GlcNAc-T III) catalyzes the incorporation of a "bisecting" N-acetylglucosamine (GlcNAc) residue in beta 1-4 linkage to the beta-linked mannose of the core of asparagine linked-protein bound oligosaccharides (N-glycans). n-glycans 285-294 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 77-89 29502191-9 2018 The presence of these unusual complex N-glycans resulted in stronger interactions of cellular glycoproteins with the PHA-L. Based on the data presented here we conclude that elevated activity of GnT-III in cancer cells does not necessarily lead to a total abrogation of the formation of highly branched glycans. n-glycans 38-47 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 195-202 32348856-8 2020 Furthermore, co-expressing MGAT3 generated N-glycans likely bearing bisected GlcNAc. n-glycans 43-52 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 27-32 26801611-1 2016 N-Acetylglucosaminyltransferase III (GnT-III), which catalyzes the addition of the bisecting GlcNAc branch on N-glycans, is usually described as a metastasis suppressor. n-glycans 110-119 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 27429195-3 2016 Bisecting GlcNAc is attached to N-glycans through beta 1-4 N-acetylglucosaminyl transferase III (MGAT3), which is encoded by two exons flanked by high-density CpG islands. n-glycans 32-41 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 97-102 26801611-1 2016 N-Acetylglucosaminyltransferase III (GnT-III), which catalyzes the addition of the bisecting GlcNAc branch on N-glycans, is usually described as a metastasis suppressor. n-glycans 110-119 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 25936519-5 2015 HS5 cells had significantly enhanced levels of bisecting N-glycans (catalyzed by MGAT3 [beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase]), whereas HS27a cells had enhanced levels of Galbeta1,4GlcNAc (catalyzed by beta4GalT1 [beta4-galactosyltransferase I]). n-glycans 57-66 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 81-86 25936519-5 2015 HS5 cells had significantly enhanced levels of bisecting N-glycans (catalyzed by MGAT3 [beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase]), whereas HS27a cells had enhanced levels of Galbeta1,4GlcNAc (catalyzed by beta4GalT1 [beta4-galactosyltransferase I]). n-glycans 57-66 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 88-157 24855066-10 2014 For the first time, we provide evidence that MGAT3 expression may be epigenetically regulated by DNA hypomethylation, leading to the synthesis of the unique "bisecting GlcNAc" type N-glycans on the membrane proteins of ovarian cancer cells. n-glycans 181-190 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 45-50 26109616-2 2015 SUMMARY ANSWER: The dynamic balance between GnT-V and GnT-III expression in chorionic villi differed between early normal pregnancy and ESM and was associated with altered beta1,6-N-acetylglucosamine (beta1,6-GlcNAc) and bisecting N-acetylglucosamine (bis-GlcNAc) branched N-glycans on integrin beta1. n-glycans 273-282 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 54-61 24037315-1 2013 Bisected, complex N-glycans on glycoproteins are generated by the glycosyltransferase MGAT3 and cause reduced cell surface binding of galectins. n-glycans 18-27 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 86-91 22451656-3 2012 Treatment with TGF-beta1 resulted in a decrease in E-cadherin expression and GnT-III expression, as well as its product, the bisected N-glycans, which was confirmed by erythro-agglutinating phytohemagglutinin lectin blot and HPLC analysis in human MCF-10A and mouse GE11 cells. n-glycans 134-143 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 77-84 23671930-5 2013 METHODS: In the present study, we have characterized the functional implications of the N-glycans catalyzed by GnT-III and GnT-V on the regulation of E-cadherin biological functions and in the molecular assembly and stability of adherens-junctions in a gastric cancer model. n-glycans 88-97 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 111-118 20083147-2 2010 The beta1,4-N-acetylglucosaminyltransferase III (GnTIII) introduces a bisecting GlcNAc residue into N-glycans, which exerts a high level of substrate mediated control over subsequent modifications, for example inhibiting mammalian core fucosylation. n-glycans 100-109 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 49-55 21115490-8 2011 Unexpectedly, shRNA knockdown of beta-catenin resulted in a dramatic increase in GnT-III expression and its product, the bisected N-glycans, which was confirmed by RT-PCR and GnT-III activity and by E4-PHA lectin blot analysis. n-glycans 130-139 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 81-88 20395209-2 2010 The addition of the bisecting GlcNAc to complex N-glycans by Mgat3 has varying effects on cell adhesion, cell migration, and hepatoma formation. n-glycans 48-57 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 61-66 22427986-1 2012 BACKGROUND: N-acetylglucosaminyltransferase-III (GnT-III) is a glycosyltransferase encoded by Mgat3 that catalyzes the addition of beta1,4-bisecting-N-acetylglucosamine on N-glycans. n-glycans 172-181 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 12-47 22427986-1 2012 BACKGROUND: N-acetylglucosaminyltransferase-III (GnT-III) is a glycosyltransferase encoded by Mgat3 that catalyzes the addition of beta1,4-bisecting-N-acetylglucosamine on N-glycans. n-glycans 172-181 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 49-56 22427986-1 2012 BACKGROUND: N-acetylglucosaminyltransferase-III (GnT-III) is a glycosyltransferase encoded by Mgat3 that catalyzes the addition of beta1,4-bisecting-N-acetylglucosamine on N-glycans. n-glycans 172-181 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 94-99 20554946-5 2010 As evidenced by structural analyses of N-glycans prepared from whole cells and the expressed recombinant glycoproteins, the introduction of GnT-III led to the production of bisected hybrid-type N-glycans in which the beta1,2-GlcNAc residue at the alpha1,3-mannosyl branch is completely retained and which has the potential to be present in mammalian cells. n-glycans 39-48 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 140-147 20554946-5 2010 As evidenced by structural analyses of N-glycans prepared from whole cells and the expressed recombinant glycoproteins, the introduction of GnT-III led to the production of bisected hybrid-type N-glycans in which the beta1,2-GlcNAc residue at the alpha1,3-mannosyl branch is completely retained and which has the potential to be present in mammalian cells. n-glycans 194-203 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 140-147 20083147-4 2010 The N-glycans produced by the cells expressing GnTIII were partially bisected and practically devoid of the paucimannosidic type which is typical for N-glycans produced by wildtype BY-2 suspension cultured cells. n-glycans 4-13 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 47-53 20083147-4 2010 The N-glycans produced by the cells expressing GnTIII were partially bisected and practically devoid of the paucimannosidic type which is typical for N-glycans produced by wildtype BY-2 suspension cultured cells. n-glycans 150-159 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 47-53 20083147-5 2010 The proportion of human-compatible N-glycans devoid of fucose and xylose could be increased from an average of 4% on secreted protein from wildtype cells to as high as 59% in cells expressing chimeric GnTIII, named GnTIII(A.th.) n-glycans 35-44 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 201-207 20083147-5 2010 The proportion of human-compatible N-glycans devoid of fucose and xylose could be increased from an average of 4% on secreted protein from wildtype cells to as high as 59% in cells expressing chimeric GnTIII, named GnTIII(A.th.) n-glycans 35-44 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 215-221 19403558-3 2009 N-acetylglucosaminyltransferase III (GnT-III) catalyzes the formation of a bisecting GlcNAc structure in N-glycans, and has been pointed as a metastasis suppressor. n-glycans 105-114 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 20816221-1 2010 N-acetylglucosaminyltransferase III (GnT-III) transfers N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to core mannose with a beta1,4 linkage, so-called bisecting GlcNAc, in N-glycans. n-glycans 172-181 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 20816221-1 2010 N-acetylglucosaminyltransferase III (GnT-III) transfers N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to core mannose with a beta1,4 linkage, so-called bisecting GlcNAc, in N-glycans. n-glycans 172-181 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 20816221-7 2010 In fact, overexpression of GnT-III reduced the beta1,6 GlcNAc branching structures, in conjunction with the increase in the bisected N-glycans on integrins, and resulted in an inhibition of integrin-mediated cell spreading and migration, and the cellular phosphorylation levels. n-glycans 133-142 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 27-34 19403558-3 2009 N-acetylglucosaminyltransferase III (GnT-III) catalyzes the formation of a bisecting GlcNAc structure in N-glycans, and has been pointed as a metastasis suppressor. n-glycans 105-114 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 19403558-7 2009 We also showed that GnT-III and GnT-V competitively modified E-cadherin N-glycans. n-glycans 72-81 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 20-27 19403558-9 2009 Further, the GnT-III knockdown cells also caused modifications of E-cadherin N-glycans catalyzed by GnT-III and GnT-V. n-glycans 77-86 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 13-20 19403558-9 2009 Further, the GnT-III knockdown cells also caused modifications of E-cadherin N-glycans catalyzed by GnT-III and GnT-V. n-glycans 77-86 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 100-107 18812317-6 2008 By contrast, bisecting GlcNAc catalyzed by N-acetylglucosaminyltransferase III (GnT-III) suppresses the further processing with branching enzymes, such as GnT-V, and the elongation of N-glycans. n-glycans 184-193 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 43-78 19420742-4 2009 Here, we focus mainly on the modification of N-glycans with N-acetylglucosaminyltransferase III (GnT-III), N-acetylglucosaminyltransferase V (GnT-V) and alpha2,6 sialyltransferase (ST6GalI) to address the important roles of N-glycans in integrin-meditaed cell adhesion and migration. n-glycans 45-54 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 97-104 18812317-6 2008 By contrast, bisecting GlcNAc catalyzed by N-acetylglucosaminyltransferase III (GnT-III) suppresses the further processing with branching enzymes, such as GnT-V, and the elongation of N-glycans. n-glycans 184-193 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 80-87 18812317-8 2008 Lectin blotting and mass spectrometry analyses revealed that N-glycans containing the bisecting GlcNAc and beta1,6-GlcNAc structures were strongly expressed on Lm332 purified from GnT-III-overexpressing (GnT-III-Lm332) and GnT-V-overexpressing (GnT-V-Lm332) cells, respectively. n-glycans 61-70 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 180-187 18812317-8 2008 Lectin blotting and mass spectrometry analyses revealed that N-glycans containing the bisecting GlcNAc and beta1,6-GlcNAc structures were strongly expressed on Lm332 purified from GnT-III-overexpressing (GnT-III-Lm332) and GnT-V-overexpressing (GnT-V-Lm332) cells, respectively. n-glycans 61-70 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 204-211 16940045-2 2006 N-acetylglucosaminyltransferase III (GnT-III) catalyzes the formation of a bisecting GlcNAc structure in N-glycans, resulting in the suppression of metastasis. n-glycans 105-114 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 18690644-2 2008 We found that N-acetylglucosaminyltransferase III (GnT-III) activity, and thus, the enzyme product-bisected N-glycans were induced in cells cultured under dense condition in an E-cadherin-dependent manner. n-glycans 108-117 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 14-49 18690644-2 2008 We found that N-acetylglucosaminyltransferase III (GnT-III) activity, and thus, the enzyme product-bisected N-glycans were induced in cells cultured under dense condition in an E-cadherin-dependent manner. n-glycans 108-117 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 51-58 17179169-0 2007 Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III. n-glycans 64-73 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 115-150 17179169-4 2007 These analyses revealed that most of the complex-type N-glycans in the plants expressing GnT-III were bisected and carried at least two terminal N-acetylglucosamine (GlcNAc) residues in contrast to wild-type plants, where a considerable proportion of N-glycans did not contain GlcNAc residues at the nonreducing end. n-glycans 54-63 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 89-96 17179169-4 2007 These analyses revealed that most of the complex-type N-glycans in the plants expressing GnT-III were bisected and carried at least two terminal N-acetylglucosamine (GlcNAc) residues in contrast to wild-type plants, where a considerable proportion of N-glycans did not contain GlcNAc residues at the nonreducing end. n-glycans 251-260 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 89-96 17179169-5 2007 Moreover, we have shown that the majority of N-glycans of an antibody produced in a plant expressing GnT-III is also bisected. n-glycans 45-54 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 101-108 16940045-2 2006 N-acetylglucosaminyltransferase III (GnT-III) catalyzes the formation of a bisecting GlcNAc structure in N-glycans, resulting in the suppression of metastasis. n-glycans 105-114 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 16940045-7 2006 Consistently, an increase in bisected GlcNAc but a decrease in beta1,6-GlcNAc-branched N-glycans on integrin alpha3 subunit was observed in the double transfectants of GnT-III and GnT-V. n-glycans 87-96 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 168-175 16940045-8 2006 Conversely, GnT-III knockdown resulted in increased migration on laminin 5, concomitant with an increase in beta1,6-GlcNAc-branched N-glycans on the alpha3 subunit in CHP134 cells, a human neuroblastoma cell line. n-glycans 132-141 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 12-19 11784313-1 2002 beta 1,4-N-Acetylglucosaminyltransferase III (GnT-III) plays a regulatory role in the biosynthesis of N-glycans, and it has been suggested that its product, a bisecting GlcNAc, is involved in a variety of biological events as well as in regulating the biosynthesis of the oligosaccharides. n-glycans 102-111 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 46-53 15187417-1 2004 N-Acetylglucosaminyltransferase III (GnT-III), which catalyzes the synthesis of a bisecting GlcNAc residue of N-glycans, is thought to be involved in the function of glycoproteins such as growth factor receptors. n-glycans 110-119 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 15187417-1 2004 N-Acetylglucosaminyltransferase III (GnT-III), which catalyzes the synthesis of a bisecting GlcNAc residue of N-glycans, is thought to be involved in the function of glycoproteins such as growth factor receptors. n-glycans 110-119 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 12716887-4 2003 Because the addition of a bisecting GlcNAc by GnT-III to the core beta-Man in N-glycans prevents the action of GnT-IV and GnT-V, both of which are involved in branch formation, this result suggests that caveolin-1 facilitates the prior action of GnT-III, relative to the other GnTs, on the nascent sugar chains in the Golgi apparatus and that GnT-III is redistributed in the earlier Golgi subcompartment by caveolin-1. n-glycans 78-87 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 46-53 12716887-4 2003 Because the addition of a bisecting GlcNAc by GnT-III to the core beta-Man in N-glycans prevents the action of GnT-IV and GnT-V, both of which are involved in branch formation, this result suggests that caveolin-1 facilitates the prior action of GnT-III, relative to the other GnTs, on the nascent sugar chains in the Golgi apparatus and that GnT-III is redistributed in the earlier Golgi subcompartment by caveolin-1. n-glycans 78-87 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 246-253 12716887-4 2003 Because the addition of a bisecting GlcNAc by GnT-III to the core beta-Man in N-glycans prevents the action of GnT-IV and GnT-V, both of which are involved in branch formation, this result suggests that caveolin-1 facilitates the prior action of GnT-III, relative to the other GnTs, on the nascent sugar chains in the Golgi apparatus and that GnT-III is redistributed in the earlier Golgi subcompartment by caveolin-1. n-glycans 78-87 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 246-253 12427758-1 2003 N-acetylglucosaminyltransferase III (GnT-III) is a key enzyme that inhibits the extension of N-glycans by introducing a bisecting N-acetylglucosamine residue. n-glycans 93-102 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 12427758-1 2003 N-acetylglucosaminyltransferase III (GnT-III) is a key enzyme that inhibits the extension of N-glycans by introducing a bisecting N-acetylglucosamine residue. n-glycans 93-102 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 12427758-2 2003 Our previous studies have shown that modification of N-glycans by GnT-III affects a number of intracellular signaling pathways. n-glycans 53-62 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 66-73 11784313-4 2002 The overexpression of Asp323-substituted, catalytically inactive GnT-III in Huh6 cells led to the suppression of the activity of endogenous GnT-III, but no significant decrease in its expression, and led to a specific inhibition of the formation of bisected sugar chains, as shown by structural analysis of the total N-glycans from the cells. n-glycans 317-326 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 65-72 10640395-6 2000 These results suggest that GnT-III activity undergoes a cell-cycle-dependent regulation and thereby oligosaccharide structures of N-glycans vary specifically during the M phase of the cell cycle. n-glycans 130-139 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 27-34 11134020-1 2001 N-Acetylglucosaminyltransferase III (GnT-III) is a key enzyme that inhibits the extension of N-glycans by introducing a bisecting N-acetylglucosamine residue. n-glycans 93-102 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 0-35 11134020-1 2001 N-Acetylglucosaminyltransferase III (GnT-III) is a key enzyme that inhibits the extension of N-glycans by introducing a bisecting N-acetylglucosamine residue. n-glycans 93-102 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 37-44 11501752-11 2001 These findings were compatible with the structural changes of N-glycans in BCa Fn, since GnT-III and GnT-IV/V are responsible for the synthesis of bisecting GlcNAc and the increase of antennary number in N-glycans, respectively. n-glycans 62-71 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 89-96 11501752-11 2001 These findings were compatible with the structural changes of N-glycans in BCa Fn, since GnT-III and GnT-IV/V are responsible for the synthesis of bisecting GlcNAc and the increase of antennary number in N-glycans, respectively. n-glycans 204-213 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 89-96 10640395-7 2000 Thus, it is possible that the cell-cycle-dependent alteration of N-glycans by GnT-III might play a role in biological events, such as the progression of cell cycle and cell division. n-glycans 65-74 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 78-85 9680100-9 1998 The increase of GlcNAc T-III activity and bis-GlcNAc content in N-glycans may be related to cell adhesion observed in monocytic differentiation. n-glycans 64-73 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 16-28 34495528-9 2021 N-Acetylglucosaminyltransferases (GnT-III, GnT-IV, and GnT-V) produce branched N-glycan structures, affording a higher complexity to N-glycans. n-glycans 133-142 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Homo sapiens 34-41