PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20206280-0 2010 Mgat1-dependent N-glycans are essential for the normal development of both vertebrate and invertebrate metazoans. n-glycans 16-25 mannoside acetylglucosaminyltransferase 1 Mus musculus 0-5 32591389-6 2020 Elimination of branched N-glycans in developing B cells via targeted deletion of N-acetylglucosaminyl transferase I (Mgat1) markedly reduced cellularity in the bone marrow and/or spleen and inhibited maturation of pre-, immature, and transitional stage 2 B cells. n-glycans 24-33 mannoside acetylglucosaminyltransferase 1 Mus musculus 117-122 29386567-3 2018 MGAT1 is the N-acetylglucosaminyltransferase (GlcNAcT-I) that initiates the synthesis of complex N-glycans. n-glycans 97-106 mannoside acetylglucosaminyltransferase 1 Mus musculus 0-5 29386567-3 2018 MGAT1 is the N-acetylglucosaminyltransferase (GlcNAcT-I) that initiates the synthesis of complex N-glycans. n-glycans 97-106 mannoside acetylglucosaminyltransferase 1 Mus musculus 46-55 21834068-8 2011 The expression of beta1,2N-acetylglucosaminyltransferase I (GlcNAc-TI) mRNA, which converts high-mannose type N-glycans, was significantly increased in degraded mouse cartilage. n-glycans 110-119 mannoside acetylglucosaminyltransferase 1 Mus musculus 60-69 9867843-2 1999 Studies on mice with a null mutation in the GnT I gene have indicated that N-glycans play critical roles in mammalian morphogenesis. n-glycans 75-84 mannoside acetylglucosaminyltransferase 1 Mus musculus 44-49 17883406-2 2008 The products of Golgi UDP-GlcNAc:N-acetylglucosaminyltransferases (encoded by Mgat1, Mgat2, Mgat4 and Mgat5) act sequentially to generate the GlcNAc-branched complex-type N-glycans on glycoprotein receptors. n-glycans 171-180 mannoside acetylglucosaminyltransferase 1 Mus musculus 78-83 17883406-3 2008 While elimination of all the branched N-glycans in Mgat1(-/-) mouse embryos is lethal at neural tube fold stage, decreased branching is associated with late developmental defects similar to type 2 of congenital disorders of glycosylation, with developmental and psychomotor abnormalities. n-glycans 38-47 mannoside acetylglucosaminyltransferase 1 Mus musculus 51-56 17374637-3 2007 However, Mgat1(-/-) eggs with modified N-glycans lacking terminal Gal and GlcNAc residues are fertilized. n-glycans 39-48 mannoside acetylglucosaminyltransferase 1 Mus musculus 9-14 1533386-4 1992 UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (EC 2.4.1.101; GlcNAc-TI) is a key enzyme in the process because it is essential for the conversion of high-mannose N-glycans to complex and hybrid N-glycans. n-glycans 203-212 mannoside acetylglucosaminyltransferase 1 Mus musculus 102-111 1447191-1 1992 UDP-GlcNAc:alpha 3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I (GnTI) is an N(in)/C(out) (type II) membrane protein, localized in the medial-Golgi, that initiates the conversion of high mannose N-glycans to complex N-glycans. n-glycans 205-214 mannoside acetylglucosaminyltransferase 1 Mus musculus 0-73 1447191-1 1992 UDP-GlcNAc:alpha 3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I (GnTI) is an N(in)/C(out) (type II) membrane protein, localized in the medial-Golgi, that initiates the conversion of high mannose N-glycans to complex N-glycans. n-glycans 205-214 mannoside acetylglucosaminyltransferase 1 Mus musculus 75-79 1447191-1 1992 UDP-GlcNAc:alpha 3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I (GnTI) is an N(in)/C(out) (type II) membrane protein, localized in the medial-Golgi, that initiates the conversion of high mannose N-glycans to complex N-glycans. n-glycans 226-235 mannoside acetylglucosaminyltransferase 1 Mus musculus 0-73 1447191-1 1992 UDP-GlcNAc:alpha 3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I (GnTI) is an N(in)/C(out) (type II) membrane protein, localized in the medial-Golgi, that initiates the conversion of high mannose N-glycans to complex N-glycans. n-glycans 226-235 mannoside acetylglucosaminyltransferase 1 Mus musculus 75-79 9363433-0 1997 Complex N-glycans in Mgat1 null preimplantation embryos arise from maternal Mgat1 RNA. n-glycans 8-17 mannoside acetylglucosaminyltransferase 1 Mus musculus 21-26 9363433-0 1997 Complex N-glycans in Mgat1 null preimplantation embryos arise from maternal Mgat1 RNA. n-glycans 8-17 mannoside acetylglucosaminyltransferase 1 Mus musculus 76-81 9363433-3 1997 However, inner cell mass of all blastocysts from several Mgat1 +/- heterozygous crosses bind the lectin E-PHA, indicating that Mgat1 null mutant blastocysts are able to synthesize complex N-glycans (Campbell et al., (1995) Glycobiology, 5, 535-543). n-glycans 188-197 mannoside acetylglucosaminyltransferase 1 Mus musculus 127-132 9020882-1 1997 UDP-GlcNAc: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (EC 2.4.1.101; GlcNAc-T I) is a medial-Golgi enzyme which catalyses the first step in the conversion of oligomannose-type to N-acetyl-lactosamine- and hybrid-type N-glycans and is essential for normal embryogenesis in the mouse. n-glycans 238-247 mannoside acetylglucosaminyltransferase 1 Mus musculus 90-100 8855305-1 1996 Mice lacking the complex subset of N-glycans due to inactivation of the Mgat1 gene die at mid-gestation, making it difficult to identify specific biological functions for this class of cell surface carbohydrates. n-glycans 35-44 mannoside acetylglucosaminyltransferase 1 Mus musculus 72-77 8855305-3 1996 The Mgat1 gene encodes N-acetylglucosaminyltransferase I (Glc-NAc-TI; EC 2.4.1.101), the transferase that initiates the synthesis of complex N-glycans. n-glycans 141-150 mannoside acetylglucosaminyltransferase 1 Mus musculus 4-9 8855305-3 1996 The Mgat1 gene encodes N-acetylglucosaminyltransferase I (Glc-NAc-TI; EC 2.4.1.101), the transferase that initiates the synthesis of complex N-glycans. n-glycans 141-150 mannoside acetylglucosaminyltransferase 1 Mus musculus 58-68 8563140-6 1995 However, apparently normal levels of complex N-glycans were observed in E3.5 pre-implantation Mgat1-null embryos prior to declining to undetectable levels by E7.5. n-glycans 45-54 mannoside acetylglucosaminyltransferase 1 Mus musculus 94-99 8563140-8 1995 Mgat1-null embryos appear to complete pre-implantation development in the presence of maternally derived complex N-glycans, and may die at later stages, post E7.5, when a requirement for embryonically derived complex N-glycans arises. n-glycans 113-122 mannoside acetylglucosaminyltransferase 1 Mus musculus 0-5 8563140-8 1995 Mgat1-null embryos appear to complete pre-implantation development in the presence of maternally derived complex N-glycans, and may die at later stages, post E7.5, when a requirement for embryonically derived complex N-glycans arises. n-glycans 217-226 mannoside acetylglucosaminyltransferase 1 Mus musculus 0-5