PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35164559-2 2022 These N-glycans are predicted to modulate spike binding to the host receptor by stabilizing its open conformation and host immunity evasion. n-glycans 6-15 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 42-47 33140034-6 2020 We reveal an essential structural role of N-glycans at sites N165 and N234 in modulating the conformational dynamics of the spike"s receptor binding domain (RBD), which is responsible for ACE2 recognition. n-glycans 42-51 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 124-129 34494876-14 2021 In addition, we found that the removal of N-glycans of ACE2 impaired its ability to support an efficient transduction of SARS-CoV and SARS-CoV-2 S pseudotyped viruses. n-glycans 42-51 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 145-146 34735575-4 2022 Despite maintaining an overall similar structural conformation, our mass spectrometry-based site-specific glycosylation analyses of similarly produced spike proteins with and without the D614G and Alpha variant mutations reveal a significant shift in the processing state of N-glycans on one specific NTD site. n-glycans 275-284 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 151-156 34485255-4 2021 Here, we expressed the transmembrane-deleted human beta-1,2 N-acetlyglucosamintransferases I and II (MGAT1DeltaTM and MGAT2DeltaTM) and the beta-1,4-galactosyltransferase (GalTDeltaTM) in E. coli to in-vitro remodel the N-glycans of a recombinant SARS-CoV-2 spike glycoprotein derived from insect cells. n-glycans 220-229 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 258-263 34291736-3 2021 Here, we report that the C-type lectin receptor L-SIGN interacted in a Ca2+-dependent manner with high-mannose-type N-glycans on the SARS-CoV-2 spike protein. n-glycans 116-125 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 144-149 35164559-9 2022 Spike proteins are heavily modified with several N-glycans, which are predicted to modulate their function. n-glycans 49-58 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 0-5