PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31882567-1	2020	Diabetes triggers peripheral nerve alterations at a structural and functional level, collectively referred to as Diabetic Peripheral Neuropathy (DPN).This work highlights the role of the oxysterol/LXR signaling pathway and the crosstalk with the reactive oxygen species (ROS) producing enzyme, NADPH oxidase-4 (Nox4) in the pathogenesis of DPN.Herein, we assess behavioral, molecular and physio-pathological changes in cultured Schwann cells as well as in the sciatic nerve of a type 1 diabetic (T1DM) murine model, and skin biopsies from type 2 diabetic (T2DM) patients.T1DM animals exhibit neurophysiological defects and sensorimotor abnormalities paralleled by a defective peripheral myelin genes expression in MPZ and PMP22.	arthrofactin	187-196	peripheral myelin protein 22	Homo sapiens	722-727