PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29085514-0 2017 Protective role of LRRC3B in preventing breast cancer metastasis and recurrence post-bupivacaine. Bupivacaine 85-96 leucine rich repeat containing 3B Homo sapiens 19-25 29085514-5 2017 The influence of bupivacaine on LRRC3B expression was measured based on RT-qPCR. Bupivacaine 17-28 leucine rich repeat containing 3B Homo sapiens 32-38 29085514-6 2017 Additionally, the effect of LRRC3B silencing on the invasion of breast cancer cells treated with bupivacaine was analyzed. Bupivacaine 97-108 leucine rich repeat containing 3B Homo sapiens 28-34 29085514-8 2017 The administration of 50 microg/ml bupivacaine promoted maximum breast cancer cell invasion, and suppressed LRRC3B mRNA expression in cells. Bupivacaine 35-46 leucine rich repeat containing 3B Homo sapiens 108-114 29085514-9 2017 However, when LRRC3B was silenced in cancer cells, 20 microg/ml bupivacaine significantly promoted cancer cell invasion, indicating that bupivacaine suppresses the expression of LRRC3B and promotes cell invasion. Bupivacaine 64-75 leucine rich repeat containing 3B Homo sapiens 14-20 29085514-9 2017 However, when LRRC3B was silenced in cancer cells, 20 microg/ml bupivacaine significantly promoted cancer cell invasion, indicating that bupivacaine suppresses the expression of LRRC3B and promotes cell invasion. Bupivacaine 64-75 leucine rich repeat containing 3B Homo sapiens 178-184 29085514-9 2017 However, when LRRC3B was silenced in cancer cells, 20 microg/ml bupivacaine significantly promoted cancer cell invasion, indicating that bupivacaine suppresses the expression of LRRC3B and promotes cell invasion. Bupivacaine 137-148 leucine rich repeat containing 3B Homo sapiens 14-20 29085514-9 2017 However, when LRRC3B was silenced in cancer cells, 20 microg/ml bupivacaine significantly promoted cancer cell invasion, indicating that bupivacaine suppresses the expression of LRRC3B and promotes cell invasion. Bupivacaine 137-148 leucine rich repeat containing 3B Homo sapiens 178-184 29085514-10 2017 The present study suggested that LRRC3B serves a protective role in preventing bupivacaine-induced breast cancer recurrence and metastasis. Bupivacaine 79-90 leucine rich repeat containing 3B Homo sapiens 33-39