PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10534314-2	1999	Biotransformation of propofol to 2,6-diisopropyl-1,4-quinol (4-hydroxypropofol) by cytochrome P-450 in the liver is proposed as a critical initial step in the elimination of this drug in dogs.	Propofol	21-29	Cytochrome P450 1A1	Canis lupus familiaris	83-99	
10534314-9	1999	These results indicate that there are breed differences in propofol hydroxylase activity and that deficient hydroxylation of propofol by one or more hepatic cytochrome P-450 isoforms may contribute to slow pharmacokinetic clearance of propofol by greyhounds.	Propofol	59-67	Cytochrome P450 1A1	Canis lupus familiaris	157-173	
10534314-9	1999	These results indicate that there are breed differences in propofol hydroxylase activity and that deficient hydroxylation of propofol by one or more hepatic cytochrome P-450 isoforms may contribute to slow pharmacokinetic clearance of propofol by greyhounds.	Propofol	125-133	Cytochrome P450 1A1	Canis lupus familiaris	157-173