PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18292429-0	2008	Molecular actions of propofol on human 5-HT3A receptors: enhancement as well as inhibition by closely related phenol derivatives.	Propofol	21-29	5-hydroxytryptamine receptor 3A	Homo sapiens	39-45	
18292429-3	2008	To investigate the molecular mechanisms responsible for these contrasting actions, we examined the kinetics of the action of propofol and its lesser hydrophobic derivatives 2-isopropylphenol and phenol on human 5-HT3A receptors.	Propofol	125-133	5-hydroxytryptamine receptor 3A	Homo sapiens	211-217	
18292429-6	2008	RESULTS: When applied in equilibrium (60 s before and during the 5-HT pulse), propofol inhibited human 5-HT3A receptors (IC50 = 18 +/- 1.0 microM).	Propofol	78-86	5-hydroxytryptamine receptor 3A	Homo sapiens	103-109	
18292429-12	2008	CONCLUSIONS: At least two separate inhibitory actions on 5-HT3A receptors could be identified for propofol, whereas the enhancing action seen for the two related smaller phenol derivatives could no longer be detected.	Propofol	98-106	5-hydroxytryptamine receptor 3A	Homo sapiens	57-63	
17669396-0	2007	Inhibition of human 5-HT(3A) and 5-HT(3AB) receptors by etomidate, propofol and pentobarbital.	Propofol	67-75	5-hydroxytryptamine receptor 3A	Homo sapiens	20-27	
17669396-4	2007	Because the half-maximal inhibitory concentrations for etomidate, propofol and pentobarbital in 5-HT(3A) and 5-HT(3AB) receptors were all above their respective anaesthetic concentrations, the results of our study suggest that neither 5-HT(3) receptor subtype contributes to the anaesthetic actions of etomidate, propofol or pentobarbital.	Propofol	66-74	5-hydroxytryptamine receptor 3A	Homo sapiens	96-103