PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25105067-2 2014 Here, we wanted to determine if propofol can also activate the Janus kinase (JAK) 2/signal transducer and activator of transcription (STAT) 3 pathway, another branch of cardioprotective signaling. Propofol 32-40 Janus kinase 2 Rattus norvegicus 63-83 27998796-0 2017 Propofol postconditioning attenuates hippocampus ischemia-reperfusion injury via modulating JAK2/STAT3 pathway in rats after autogenous orthotropic liver transplantation. Propofol 0-8 Janus kinase 2 Rattus norvegicus 92-96 27998796-5 2017 In this study we investigate whether propofol plays an important role in protecting the hippocampus through JAK2/STAT3 pathway. Propofol 37-45 Janus kinase 2 Rattus norvegicus 108-112 27998796-10 2017 However, an induction of propofol reduced the levels of MDA, TNFalpha, S100beta, NSE and increased activity of SOD, IL-10, and attenuated the expression of JAK2 and STAT3, meanwhile. Propofol 25-33 Janus kinase 2 Rattus norvegicus 156-160 27998796-13 2017 Pretreatment with propofol attenuates autogenous orthotropic liver transplantation induces hippocampal injury via JAK2/STAT3 pathway. Propofol 18-26 Janus kinase 2 Rattus norvegicus 114-118 25105067-10 2014 Conversely, pretreatment with JAK2/STAT3 pathway inhibitor AG490 or stattic inhibited propofol-induced AKT phosphorylation. Propofol 86-94 Janus kinase 2 Rattus norvegicus 30-34 25105067-13 2014 Our results suggest that propofol induces an adaptive response by dual activation and crosstalk of cytoprotective PI3K/AKT and JAK2/STAT3 pathways. Propofol 25-33 Janus kinase 2 Rattus norvegicus 127-131 31364140-14 2019 According to the results of Western blotting, the relative protein expression levels of p-JAK2 and p-STAT3 proteins were remarkably elevated in the model group, propofol group and inhibitor group in comparison with those in the sham-operation group (p<0.05). Propofol 161-169 Janus kinase 2 Rattus norvegicus 90-94 31364140-15 2019 Propofol group and inhibitor group exhibited remarkably lower protein expression levels of p-JAK2 and p-STAT3 compared with the model group (p<0.05). Propofol 0-8 Janus kinase 2 Rattus norvegicus 93-97