PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11051618-1 2000 The activity of mecillinam, a beta-lactam antibiotic with high affinity for gram-negative penicillin-binding protein 2 (PBP2), was assessed against ampicillin-resistant Escherichia coli strains producing beta-lactamases representing the three molecular classes, A (TEM-1 and -3, SHV-3 and IRT-5), C (AmpC) and D (OXA-3). Amdinocillin 16-26 hypothetical protein Escherichia coli 265-284 28369441-0 2017 A combination of mecillinam and amoxicillin/clavulanate can restore susceptibility of high-level TEM-1-producing Escherichia coli to mecillinam. Amdinocillin 17-27 hypothetical protein Escherichia coli 97-102 28369441-0 2017 A combination of mecillinam and amoxicillin/clavulanate can restore susceptibility of high-level TEM-1-producing Escherichia coli to mecillinam. Amdinocillin 133-143 hypothetical protein Escherichia coli 97-102 3061383-6 1988 In vitro activity of TEM-1 E. coli to mecillinam was strongly reduced when tested in a broth dilution technique. Amdinocillin 38-48 hypothetical protein Escherichia coli 21-26 10969046-1 2000 The activity of mecillinam, a beta-lactam antibiotic with high affinity for Gram-negative penicillin-binding protein 2 (PBP2), was assessed against ampicillin-resistant Escherichia coli strains producing beta-lactamases representing the three molecular classes, A (TEM-1 and -3, SHV-3 and IRT-5), C (AmpC) and D (OXA-3). Amdinocillin 16-26 hypothetical protein Escherichia coli 265-284 3061383-0 1988 In vitro activity of mecillinam and amoxicillin/clavulanic acid against strains of Escherichia coli producing TEM-1, Oxa-1 and chromosomal beta-lactamases. Amdinocillin 21-31 hypothetical protein Escherichia coli 110-115 3061383-1 1988 The in vitro activity of mecillinam and amoxicillin/clavulanic acid against Escherichia coli strains producing beta-lactamases of the TEM-1, Oxa-1 and chromosomal type were studied using the broth and agar dilution technique. Amdinocillin 25-35 hypothetical protein Escherichia coli 134-139 3061383-4 1988 Both, mecillinam and amoxicillin/clavulanic acid were considerably more active against TEM-1 strains than ampicillin alone, but, with increasing specific beta-lactamase activity, a decrease of susceptibility was found. Amdinocillin 6-16 hypothetical protein Escherichia coli 87-92