PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3137474-0	1988	Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue.	tripeptide K-26	67-77	interleukin 1 beta	Homo sapiens	0-18	
3137474-5	1988	We have delineated the region of IL-1 beta mediating the hyperalgesic effect and developed an analgesic tripeptide analogue of IL-1 beta which antagonizes hyperalgesia evoked by IL-1 beta and by the inflammatory agent carrageenan.	tripeptide K-26	104-114	interleukin 1 beta	Homo sapiens	33-42	
3137474-5	1988	We have delineated the region of IL-1 beta mediating the hyperalgesic effect and developed an analgesic tripeptide analogue of IL-1 beta which antagonizes hyperalgesia evoked by IL-1 beta and by the inflammatory agent carrageenan.	tripeptide K-26	104-114	interleukin 1 beta	Homo sapiens	127-136	
3137474-5	1988	We have delineated the region of IL-1 beta mediating the hyperalgesic effect and developed an analgesic tripeptide analogue of IL-1 beta which antagonizes hyperalgesia evoked by IL-1 beta and by the inflammatory agent carrageenan.	tripeptide K-26	104-114	interleukin 1 beta	Homo sapiens	127-136	
20610647-8	2010	Analysis of the crystal structure of the complex between IL-1beta/IL-1R type I (IL-1RI), followed by computer modeling of KdPT and subsequent modeling of the peptide receptor complex with the crystal structure of IL-1RI via manual docking, further predicted that the tripeptide, through several H-bonds and one hydrophobic bond, interacts with the IL-1RI.	tripeptide K-26	267-277	interleukin 1 beta	Homo sapiens	57-65	
21222263-9	2010	KdPT, a derivative of KPV corresponding to IL-1beta(193-195), currently is emerging as another tripeptide with potent anti-inflammatory effects.	tripeptide K-26	95-105	interleukin 1 beta	Homo sapiens	43-51	
19016700-8	2009	CONCLUSIONS: The IL-1beta- and alpha-MSH-related tripeptide, K(D)PT, displays interesting hair pigmentation-stimulatory activities under proinflammatory conditions.	tripeptide K-26	49-59	interleukin 1 beta	Homo sapiens	17-25	
18612139-9	2008	KdPT, a derivative of KPV corresponding to amino acids 193-195 of IL-1beta, is also emerging as a tripeptide with antiinflammatory effects.	tripeptide K-26	98-108	interleukin 1 beta	Homo sapiens	66-74	
17934097-8	2007	K(D)PT, a derivative of KPV corresponding to the amino acid 193-195 of IL-1beta, is currently emerging as another tripeptide with potent anti-inflammatory effects.	tripeptide K-26	114-124	interleukin 1 beta	Homo sapiens	71-79	
16029022-2	2005	The IL-1beta(163-171) fragment known to reproduce the immunostimulatory and adjuvant effects of the whole IL-1beta without possessing any of the pro-inflammatory properties of IL-1beta was covalently anchored to the N-terminus of the Sequential Oligopeptide Carrier, SOC(n), formed by the repeating tripeptide unit Lys-Aib-Gly.	tripeptide K-26	299-309	interleukin 1 beta	Homo sapiens	4-12	
8964658-1	1995	Tripeptide and pentapeptide aldehydes as substrate-base inhibitors of cysteine proteases were designed in our laboratory for the inhibition of interleukin-1 beta converting enzyme (ICE), a recently described cysteine protease responsible for the processing of IL-1 beta.	tripeptide K-26	0-10	interleukin 1 beta	Homo sapiens	260-269	
8964658-5	1995	The tripeptide aldehyde (Z-Val-His-Asp-H) and pentapeptide aldehyde (Eoc-Ala-Tyr-Val-Ala-Asp-H) significantly reduced IL-1 beta levels in the supernatants in relatively high concentrations (10-100 microM), but the IL-1 alpha release was unaffected by these peptides.	tripeptide K-26	4-14	interleukin 1 beta	Homo sapiens	118-127	
1484875-0	1992	Food intake and body temperature responses of rats to recombinant human interleukin-1 beta and a tripeptide interleukin-1 beta antagonist.	tripeptide K-26	97-107	interleukin 1 beta	Homo sapiens	108-126	
1330615-8	1992	The carboxyl-terminal tripeptide portion of alpha-MSH may be important for the antagonistic action of alpha-MSH on the anorexia induced by IL-1.	tripeptide K-26	22-32	interleukin 1 beta	Homo sapiens	139-143