PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29183411-1 2019 The transmembrane protein, ARV1, plays a key role in intracellular sterol homeostasis by controlling sterol distribution and cellular uptake. Sterols 67-73 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 27-31 12145310-4 2002 275, 40667-40670), and thus it has been suggested that Arv1p may be involved in the trafficking of sterol in the yeast Saccharomyces cerevisiae and also in humans. Sterols 99-105 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 55-60 11063737-0 2000 Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1. Sterols 44-50 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 19-23 11063737-4 2000 Cells lacking Arv1p display altered intracellular sterol distribution and are defective in sterol uptake, consistent with a role for Arv1p in trafficking sterol into the plasma membrane. Sterols 50-56 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 14-19 11063737-4 2000 Cells lacking Arv1p display altered intracellular sterol distribution and are defective in sterol uptake, consistent with a role for Arv1p in trafficking sterol into the plasma membrane. Sterols 91-97 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 14-19 11063737-4 2000 Cells lacking Arv1p display altered intracellular sterol distribution and are defective in sterol uptake, consistent with a role for Arv1p in trafficking sterol into the plasma membrane. Sterols 91-97 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 14-19 11063737-7 2000 We propose that ARV1 is a novel mediator of eukaryotic sterol homeostasis. Sterols 55-61 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 16-20 35369708-3 2022 Med15V76R/R84K interacted with transcription factor Hap5 to improve ARV1 expression for sterol homeostasis for decreasing membrane fluidity and thereby enhancing acid tolerance. Sterols 88-94 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 68-72 29183411-1 2019 The transmembrane protein, ARV1, plays a key role in intracellular sterol homeostasis by controlling sterol distribution and cellular uptake. Sterols 101-107 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 27-31 21266578-2 2011 Yeast ARV1 mutants accumulate multiple lipids in the ER and are sensitive to pharmacological modulators of both sterol and sphingolipid metabolism. Sterols 112-118 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 6-10 23668914-1 2013 The pan-eukaryotic endoplasmic reticulum (ER) membrane protein Arv1 has been suggested to play a role in intracellular sterol transport. Sterols 119-125 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 63-67 23668914-2 2013 We tested this proposal by comparing sterol traffic in wild-type and Arv1-deficient Saccharomyces cerevisiae. Sterols 37-43 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 69-73 22142782-1 2012 The lipid transporter Arv1 regulates sterol trafficking, and glycosylphosphatidylinositol and sphingolipid biosyntheses in Saccharomyces cerevisiae. Sterols 37-43 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 22-26 21098723-7 2011 Filipin staining shows arv1 cells contain altered levels of various sterol microdomains that persist throughout the mating process. Sterols 68-74 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 23-27 18287539-7 2008 We also provide evidence that ARV1 deletion and mutations in other proteins involved in GPI anchor synthesis affect inositol phosphorylceramide synthesis as well as the intracellular distribution and amounts of sterols, suggesting a role of GPI anchor synthesis in lipid flow from the ER. Sterols 211-218 sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C 30-34