PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26938778-6 2016 Strikingly, we find miR-342-5p targets mevalonate-sterol biosynthesis using a multihit mechanism suppressing the pathway at different functional levels: transcriptionally via SREBF2, post-transcriptionally via miR-33, and enzymatically via IDI1 and SC4MOL. Sterols 50-56 microRNA 342 Homo sapiens 20-27 26938778-9 2016 The sterol pathway is known to be an integral part of the macrophage IFN antiviral response, and we show that miR-342-5p exerts broad antiviral effects against multiple, unrelated pathogenic viruses such Cytomegalovirus and Influenza A (H1N1). Sterols 4-10 microRNA 342 Homo sapiens 110-117