PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24861899-6	2014	Anti-Gb3 antibody completely blocked the binding of SAL to Raji cells but not that of OLL.	sal	52-55	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	5-8	
15744065-6	2005	Since Gb3 and both transporters in Raji cells are located in the glycosphingolipid-enriched microdomain (GEM), it is suggested that the binding of SAL to Gb3 localized in the GEM specifically induces MDR1 P-gp activation in Raji cells.	sal	147-150	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	6-9	
15744065-6	2005	Since Gb3 and both transporters in Raji cells are located in the glycosphingolipid-enriched microdomain (GEM), it is suggested that the binding of SAL to Gb3 localized in the GEM specifically induces MDR1 P-gp activation in Raji cells.	sal	147-150	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	154-157	
15738633-5	2005	SAL bound abundantly to Raji cells but not to K562 cells, and SAL binding depended on the amount of Gb3 on the cell surface.	sal	62-65	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	100-103	
19252276-2	2009	SAL uniformly bound to surfaces of Gb3-expressing (Gb3+) Burkitt"s lymphoma cells, while Gb3 molecules were interspersed on the surfaces of Gb3+ cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	35-38	
19252276-2	2009	SAL uniformly bound to surfaces of Gb3-expressing (Gb3+) Burkitt"s lymphoma cells, while Gb3 molecules were interspersed on the surfaces of Gb3+ cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	51-54	
19252276-2	2009	SAL uniformly bound to surfaces of Gb3-expressing (Gb3+) Burkitt"s lymphoma cells, while Gb3 molecules were interspersed on the surfaces of Gb3+ cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	51-54	
19252276-2	2009	SAL uniformly bound to surfaces of Gb3-expressing (Gb3+) Burkitt"s lymphoma cells, while Gb3 molecules were interspersed on the surfaces of Gb3+ cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	51-54	
19252276-4	2009	Treatment of Gb3+ cells with SAL caused an increase in binding of annexin V, however, neither caspase activation nor DNA fragmentation was observed after treatment with SAL for 22 h. Since SAL did not induce cell death in Gb3+ cells, SAL may function as an inducer of early apoptotic signal.	sal	29-32	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	13-16	
19252276-6	2009	These results suggest that SAL leads the cells to early apoptotic status via binding to Gb3 existing in GEM, and that this binding is a prerequisite condition to induce early stage of apoptosis.	sal	27-30	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	88-91	
17409683-2	2007	SAL selectively bound to Gb3 localized in glycosphingolipid-enriched microdomain (GEM) of Gb3-expressing (Gb3(+)) Burkitt"s lymphoma cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	25-28	
17409683-2	2007	SAL selectively bound to Gb3 localized in glycosphingolipid-enriched microdomain (GEM) of Gb3-expressing (Gb3(+)) Burkitt"s lymphoma cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	90-93	
17409683-2	2007	SAL selectively bound to Gb3 localized in glycosphingolipid-enriched microdomain (GEM) of Gb3-expressing (Gb3(+)) Burkitt"s lymphoma cells.	sal	0-3	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	90-93	
17409683-3	2007	Since treatment of Gb3(+) cells with SAL caused an increase in externalization of phosphatidylserine via activation of P-glycoprotein, and apoptotic volume decrease via activation of G-protein activated K(+) channel-1, SAL may function as an inducer of early apoptotic signal; however, neither caspase-8 and -3 activation nor DNA fragmentation was observed.	sal	37-40	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	19-22	
17409683-3	2007	Since treatment of Gb3(+) cells with SAL caused an increase in externalization of phosphatidylserine via activation of P-glycoprotein, and apoptotic volume decrease via activation of G-protein activated K(+) channel-1, SAL may function as an inducer of early apoptotic signal; however, neither caspase-8 and -3 activation nor DNA fragmentation was observed.	sal	219-222	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	19-22	
17409683-8	2007	Therefore, we conclude that SAL leads the cells to early apoptotic status but not late apoptotic (necrotic) status via binding to Gb3 existing in GEM, and that this binding is a prerequisite condition to induce cell cycle stop signal.	sal	28-31	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	130-133