PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31352240-8 2019 EA binds to the SphK1 and forms several interactions with catalytically important residues of ATP-binding pocket. Ellagic Acid 0-2 sphingosine kinase 1 Homo sapiens 16-21 31352240-0 2019 Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy. Ellagic Acid 14-26 sphingosine kinase 1 Homo sapiens 46-66 31352240-2 2019 Using a virtual screening approach and in vitro studies, we have identified the ellagic acid (EA), a dietary polyphenol, as a potent inhibitor of SphK1. Ellagic Acid 80-92 sphingosine kinase 1 Homo sapiens 146-151 31352240-2 2019 Using a virtual screening approach and in vitro studies, we have identified the ellagic acid (EA), a dietary polyphenol, as a potent inhibitor of SphK1. Ellagic Acid 94-96 sphingosine kinase 1 Homo sapiens 146-151 31352240-3 2019 Molecular docking study has suggested a strong binding affinity of EA to the SphK1. Ellagic Acid 67-69 sphingosine kinase 1 Homo sapiens 77-82 31352240-10 2019 Taken together, our study suggests that EA can be utilized as a chemical prototype to develop potent therapeutics targeting SphK1-associated pathologies. Ellagic Acid 40-42 sphingosine kinase 1 Homo sapiens 124-129