PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23791885-7 2013 Furthermore, ellagic acid, which inhibited E2-induced mammary tumorigenesis in our previous study, reversed the dysregulation of miR-375, miR-206, miR-182, miR-122, miR-127 and miR-183 detected with E2 treatment and modulated their target proteins (ERalpha, cyclin D1, RASD1, FoxO3a, FoxO1, cyclin G1, Bcl-w and Bcl-2). Ellagic Acid 13-25 forkhead box O1 Rattus norvegicus 284-289 31933277-7 2020 In the present study, the potent antioxidant and antiapoptotic effects of EA were indicated by the significant overexpression of SIRT1 in renal tissues that leads to significant decreases in renal MDA content, P53 protein level and forkhead-box transcription factor1 (FOXO1) expression, and significant increases in renal GSH level, catalase activity, growth arrest and DNA damage-inducible protein 45 alpha (GADDalpha45), and renal inhibition of apoptosis protein (KIAP) gene expression levels in the EA + IONP-treated group. Ellagic Acid 74-76 forkhead box O1 Rattus norvegicus 232-266 31933277-7 2020 In the present study, the potent antioxidant and antiapoptotic effects of EA were indicated by the significant overexpression of SIRT1 in renal tissues that leads to significant decreases in renal MDA content, P53 protein level and forkhead-box transcription factor1 (FOXO1) expression, and significant increases in renal GSH level, catalase activity, growth arrest and DNA damage-inducible protein 45 alpha (GADDalpha45), and renal inhibition of apoptosis protein (KIAP) gene expression levels in the EA + IONP-treated group. Ellagic Acid 74-76 forkhead box O1 Rattus norvegicus 268-273