PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16379042-3 2006 ET-743 showed the highest affinity for CYP3A4 and the highest maximal metabolic rate for CYP2D6 among the CYPs shown to metabolize ET-743. Trabectedin 0-6 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 89-95 16379042-3 2006 ET-743 showed the highest affinity for CYP3A4 and the highest maximal metabolic rate for CYP2D6 among the CYPs shown to metabolize ET-743. Trabectedin 131-137 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 89-95 12231541-8 2002 ET743 was metabolized by cDNA-expressed human CYP3A4 and to a much lesser extent by CYP2C9, CYP2D6, and CYP2E1 preparations. Trabectedin 0-5 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 92-98