PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31585271-7	2019	The UV-visible spectra showed compound 22 inhibits the formation of dopamine quinone, further the molecular docking analysis of compound 22 with tyrosinase (PDB: 2Y9X) indicated that compound 22 interacted with the amino acid residues of tyrosinase.	Dopamine	68-76	tyrosinase	Mus musculus	145-155	
31585271-7	2019	The UV-visible spectra showed compound 22 inhibits the formation of dopamine quinone, further the molecular docking analysis of compound 22 with tyrosinase (PDB: 2Y9X) indicated that compound 22 interacted with the amino acid residues of tyrosinase.	Dopamine	68-76	tyrosinase	Mus musculus	238-248	
26908040-7	2016	Tyrosinase, which catalyzes the oxidation of DA to DA quionone (DAQ), accelerated the inhibitory effect of DA on LPS-induced NO production.	Dopamine	45-47	tyrosinase	Mus musculus	0-10	
26908040-7	2016	Tyrosinase, which catalyzes the oxidation of DA to DA quionone (DAQ), accelerated the inhibitory effect of DA on LPS-induced NO production.	Dopamine	51-53	tyrosinase	Mus musculus	0-10	
23776585-1	2013	Tyrosinase, which catalyzes both the hydroxylation of tyrosine and consequent oxidation of L-DOPA to form melanin in melanocytes, is also expressed in the brain, and oxidizes L-DOPA and dopamine.	Dopamine	186-194	tyrosinase	Mus musculus	0-10	
16403784-6	2006	We also showed the protective effect of tyrosinase, which rapidly oxidizes DA and DA quinone to form stable melanin, against METH-induced dopaminergic neurotoxicity in vitro and in vivo using tyrosinase null mice.	Dopamine	75-77	tyrosinase	Mus musculus	40-50	
10987861-11	2000	These results suggest that tyrosinase controls the intracellular DA content by biosynthesis or enzymatic oxidation of DA, and the dysfunction of this activity induces cell death by elevation of intracellular DA level and consequent gradual autooxidation of DA to generate reactive oxygen species.	Dopamine	65-67	tyrosinase	Mus musculus	27-37	
12832289-0	2003	Tyrosinase: a developmentally specific major determinant of peripheral dopamine.	Dopamine	71-79	tyrosinase	Mus musculus	0-10	
12832289-1	2003	L-3,4-dihydroxyphenylalanine, the immediate precursor of dopamine, can be formed by two enzymes: tyrosine hydroxylase (TH) in catecholamine-producing neurons and chromaffin cells and tyrosinase in melanocytes.	Dopamine	57-65	tyrosinase	Mus musculus	183-193	
12832289-2	2003	In this study we examined whether tyrosinase contributes to production of dopamine.	Dopamine	74-82	tyrosinase	Mus musculus	34-44	
12832289-10	2003	The transient nature of this source of dopamine reflects a developmental switch in tyrosinase-dependent production of dopamine to production of melanin.	Dopamine	39-47	tyrosinase	Mus musculus	83-93	
12832289-10	2003	The transient nature of this source of dopamine reflects a developmental switch in tyrosinase-dependent production of dopamine to production of melanin.	Dopamine	118-126	tyrosinase	Mus musculus	83-93	
10987861-11	2000	These results suggest that tyrosinase controls the intracellular DA content by biosynthesis or enzymatic oxidation of DA, and the dysfunction of this activity induces cell death by elevation of intracellular DA level and consequent gradual autooxidation of DA to generate reactive oxygen species.	Dopamine	118-120	tyrosinase	Mus musculus	27-37	
10987861-11	2000	These results suggest that tyrosinase controls the intracellular DA content by biosynthesis or enzymatic oxidation of DA, and the dysfunction of this activity induces cell death by elevation of intracellular DA level and consequent gradual autooxidation of DA to generate reactive oxygen species.	Dopamine	118-120	tyrosinase	Mus musculus	27-37	
10987861-11	2000	These results suggest that tyrosinase controls the intracellular DA content by biosynthesis or enzymatic oxidation of DA, and the dysfunction of this activity induces cell death by elevation of intracellular DA level and consequent gradual autooxidation of DA to generate reactive oxygen species.	Dopamine	118-120	tyrosinase	Mus musculus	27-37