PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31816046-0	2020	Histidine 131 in presenilin 1 is the pH-sensitive residue that causes the increase in Abeta42 level in acidic pH.	histidine-pyridine-histidine-3	0-9	presenilin 1	Homo sapiens	17-29	
31816046-8	2020	Among the histidines facing the luminal side of presenilin (PS) 1, which is the catalytic subunit of gamma-secretase, point mutations at H131 had no effect on the Abeta42 production ratio in an acidic environment.	histidine-pyridine-histidine-3	10-20	presenilin 1	Homo sapiens	48-65	
31816046-9	2020	We also observed an increase in Abeta42 ratio when histidine was introduced into N137 of PS2, which is the corresponding residue of H131 in PS1.	histidine-pyridine-histidine-3	51-60	presenilin 1	Homo sapiens	140-143