PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19388677-1 2009 In an effort to discover novel druglike NK(1) receptor antagonists a new series of suitably substituted C-phenylpiperazine derivatives was identified by an appropriate chemical exploration of related N-phenylpiperazine analogues, with the specific aim to maximize their in vitro affinity and optimize in parallel their pharmacokinetic profile. phenylpiperazine 200-218 tachykinin receptor 1 Homo sapiens 40-54