PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22528119-9 2012 We further confirmed that Top2alpha inhibition was due to a catalytic inhibition of the enzyme because it did not induce DNA double-strand breaks in CEM-treated cells but prevented the formation of Top2alpha- rather than Top2beta-DNA covalent complexes induced by etoposide. 2-chloroethyl methyl sulfide 149-152 DNA topoisomerase II alpha Homo sapiens 26-35