PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22512261-3 2012 In the alcohol-exposed mice, the expression of 5-HT(2C) receptor mRNA increased in the ACC, caudate nucleus and putamen, dorsal raphe nucleus (DRN), hippocampus and lateral hypothalamus, while the protein level of 5-HT(2C) receptor significantly increased in the ACC. Alcohols 7-14 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 47-65 31968217-0 2020 Fluoxetine improves behavioural deficits induced by chronic alcohol treatment by alleviating RNA editing of 5-HT2C receptors. Alcohols 60-67 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 108-114 31968217-4 2020 In this study, we discovered that chronic alcohol treatment increased editing of RNA of 5-HT2CR via up-regulating the expression of ADAR2, consequently reducing the release of ATP from astrocytes induced by 5-HT2CR agonist, MK212. Alcohols 42-49 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 88-95 31968217-4 2020 In this study, we discovered that chronic alcohol treatment increased editing of RNA of 5-HT2CR via up-regulating the expression of ADAR2, consequently reducing the release of ATP from astrocytes induced by 5-HT2CR agonist, MK212. Alcohols 42-49 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 207-214 31968217-6 2020 The increased release of astroglial ATP by MK212 which was suppressed by chronic alcohol consumption, and reduction in ADAR2 activity eliminated the RNA editing of 5-HT2CR increased by alcohol in vitro and recovered the release of ATP from astrocytes induced by MK212. Alcohols 185-192 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 164-171 31968217-8 2020 Our study suggests that the astrocytic 5-HT2CR contribute to alcohol addiction; fluoxetine thus can be used to alleviate depression, treat alcohol addiction and improve motor coordination. Alcohols 61-68 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 39-46 31968217-8 2020 Our study suggests that the astrocytic 5-HT2CR contribute to alcohol addiction; fluoxetine thus can be used to alleviate depression, treat alcohol addiction and improve motor coordination. Alcohols 139-146 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 39-46 31778691-8 2020 By contrast, intra-LHb infusion of the selective 5-HT2CR agonist WAY161503 induced AB and increased c-Fos expression in the LHb in alcohol-naive but not Post-EtOH rats. Alcohols 131-138 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 49-56 22512261-3 2012 In the alcohol-exposed mice, the expression of 5-HT(2C) receptor mRNA increased in the ACC, caudate nucleus and putamen, dorsal raphe nucleus (DRN), hippocampus and lateral hypothalamus, while the protein level of 5-HT(2C) receptor significantly increased in the ACC. Alcohols 7-14 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 215-233 22512261-9 2012 administration or local injection into ACC(S) of the 5-HT(2C) receptor antagonist, SB-242084, suppressed voluntary alcohol-drinking behavior in the alcohol-exposed mice. Alcohols 117-124 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 54-72 22512261-9 2012 administration or local injection into ACC(S) of the 5-HT(2C) receptor antagonist, SB-242084, suppressed voluntary alcohol-drinking behavior in the alcohol-exposed mice. Alcohols 150-157 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 54-72