PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23543430-4 2013 Small-molecule BACE1 inhibitors of the hydroxyethylamine, hydantoin, and sulfamide classes were functionalized by biotin PEG linkers of varying lengths forming probes that were bound to streptavidin donor beads. Hydantoins 58-67 beta-secretase 1 Homo sapiens 15-20 23543430-7 2013 A probe from the hydantoin class was chosen for further optimization, where the final assay conditions of 50 nM BACE and 250 nM probe were used and Z(") values >0.75 were commonly observed. Hydantoins 17-26 beta-secretase 1 Homo sapiens 112-116