PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29500402-9 2018 However, we further found that phenytoin attenuated RIPK1 kinase activity in vitro, likely due to the hydantoin scaffold also present in necrostatin-1, and blocked upstream necrosome formation steps in the cells undergoing necroptosis. Hydantoins 102-111 receptor interacting serine/threonine kinase 1 Homo sapiens 52-57