PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22049059-0	2012	Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway.	phthalic acid	0-10	estrogen receptor 1	Homo sapiens	52-69	
22049059-6	2012	This nongenomic pathway emanated from the phthalate-induced AhR promoted tumorigenesis of ER-negative breast cancer.	phthalic acid	42-51	estrogen receptor 1	Homo sapiens	90-92	
22949852-7	2012	In human breast cancer MCF7 cells, treatment with the phthalate BBP led to demethylation of estrogen receptor (ESR1) promoter-associated CpG islands, indicating that altered ESR1 mRNA expression by BBP is due to aberrant DNA methylation.	phthalic acid	54-63	estrogen receptor 1	Homo sapiens	92-109	
22949852-7	2012	In human breast cancer MCF7 cells, treatment with the phthalate BBP led to demethylation of estrogen receptor (ESR1) promoter-associated CpG islands, indicating that altered ESR1 mRNA expression by BBP is due to aberrant DNA methylation.	phthalic acid	54-63	estrogen receptor 1	Homo sapiens	111-115	
22949852-7	2012	In human breast cancer MCF7 cells, treatment with the phthalate BBP led to demethylation of estrogen receptor (ESR1) promoter-associated CpG islands, indicating that altered ESR1 mRNA expression by BBP is due to aberrant DNA methylation.	phthalic acid	54-63	estrogen receptor 1	Homo sapiens	174-178	
14664715-3	2003	We present evidence that the EDCs bisphenol A and phthalate activate ER-mediated transcription through interaction with TRAP220.	phthalic acid	50-59	estrogen receptor 1	Homo sapiens	69-71	
16234174-3	2005	These were used to predict the binding potency to human ERalpha of four chemical groups, namely alkylphenols, phthalates, diphenylethanes and benzophenones.	phthalic acid	110-120	estrogen receptor 1	Homo sapiens	56-63	
30995175-8	2019	We then fit multivariable Cox regression models to estimate associations between phthalate exposures and incident invasive breast carcinoma according to tumor estrogen receptor status.	phthalic acid	81-90	estrogen receptor 1	Homo sapiens	159-176	
34592072-5	2021	Some phthalates bind to and activate the estrogen receptor, making them weakly estrogenic.	phthalic acid	5-15	estrogen receptor 1	Homo sapiens	41-58	
25030786-12	2014	Our results suggested that both CYP17A1 and ESR1 polymorphisms may modulate the effects of phthalate exposure on the development of leiomyoma.	phthalic acid	91-100	estrogen receptor 1	Homo sapiens	44-48	
28571686-0	2017	Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERalpha, ERbeta, and AR.	phthalic acid	38-48	estrogen receptor 1	Homo sapiens	112-119	
28571686-1	2017	Phthalate plasticizers have been reported to exert adverse effects via activation of the estrogen receptors ERalpha and ERbeta and inhibition of the androgen receptor AR as molecular initiating events.	phthalic acid	0-9	estrogen receptor 1	Homo sapiens	108-115