PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21709207-12	2011	Thus, in human EPCs, activation of PPARdelta stimulates expression and activity of GTPCH I and biosynthesis of tetrahydrobiopterin via PTEN-AKT signaling pathway.	sapropterin	111-130	phosphatase and tensin homolog	Homo sapiens	135-139	
32399044-11	2020	Conclusions: This study provides the first evidence that shear stress triggers angiogenesis in late EPCs via the PTEN/Akt/GTPCH/BH4 pathway, providing a potential nonpharmacologic therapeutic strategy for promoting angiogenesis in ischemia-related diseases.	sapropterin	128-131	phosphatase and tensin homolog	Homo sapiens	113-117