PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28866862-5 2017 SKF-525A, a widely used non-specific P450 inhibitor, had no inhibitory activity against CYP1A2, 2A6, 2E1 and 2J2, while it showed an inhibitory effect against CYP2B6, CYP2C19 and 2D6 with IC50 values of 2.5, 3.6 and 0.5 mu m, respectively. Proadifen 0-8 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 167-174 18799803-3 2008 SKF525A and its metabolite and primary amine analog all inhibited CYP2B6-, CYP2C9-, CYP2C19-, CYP2D6-, and CYP3A-selective reactions to varying degrees but had little effect on CYP1A2, CYP2A6, and CYP2E1 reactions. Proadifen 0-7 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 84-91