PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31578315-5 2019 Importantly, we found that ROCK1 was activated in an MPP+-induced PD cell model and that ROCK1 knockdown and the specific ROCK1 activation inhibitor Y-27632 blocked Drp1-mediated aberrant mitochondrial fission and apoptosis of dopaminergic nerve cells by suppressing Drp1 dephosphorylation/activation. 1-(4-methoxyphenyl)pyridinium 53-57 dynamin 1-like Mus musculus 165-169 31578315-5 2019 Importantly, we found that ROCK1 was activated in an MPP+-induced PD cell model and that ROCK1 knockdown and the specific ROCK1 activation inhibitor Y-27632 blocked Drp1-mediated aberrant mitochondrial fission and apoptosis of dopaminergic nerve cells by suppressing Drp1 dephosphorylation/activation. 1-(4-methoxyphenyl)pyridinium 53-57 dynamin 1-like Mus musculus 267-271