PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7515840-6	1994	Affinity labeling of these receptors by covalently binding them to 125I-IGF-I with disuccinimidyl suberate and subsequent electrophoretic analysis of the labeled complex revealed that the inhibitory action of TGF-beta 1 (2 ng/ml, 72 h) occurs at the level of a 135 kDa protein which represents the classical form of the binding subunit of the IGF-I receptor.	disuccinimidyl	83-97	insulin like growth factor 1	Homo sapiens	72-77	
9762008-7	1998	Affinity cross-linking with [125I]IGF-I using disuccinimidyl suberate and SDS-PAGE under reducing conditions yielded a polypeptide band with apparent Mr 130,000, consistent with the alpha-subunit of the IGF-I receptor.	disuccinimidyl	46-60	insulin like growth factor 1	Homo sapiens	34-39	
8048522-5	1994	Affinity cross-linking of cell membranes using disuccinimidyl suberate as a cross-linking agent under reducing conditions revealed a single polypeptide band (relative mol wt 133,000) representing the alpha-subunit of the IGF-I receptor.	disuccinimidyl	47-61	insulin like growth factor 1	Homo sapiens	221-226	
2156441-5	1990	Through the use of 0.5 mM disuccinimidyl suberate, 125I-IGF-II is cross-linked to a 260-kDa protein that is identified as the IGF-II receptor by displacement experiments with unlabeled IGF-II, IGF-I, and insulin and either by immunoprecipitation or by Western blot analysis with mannose 6-phosphate receptor antibodies.	disuccinimidyl	26-40	insulin like growth factor 1	Homo sapiens	56-61	
2174333-6	1990	The bioactive binding protein(s) was cross-linked with disuccinimidyl suberate to IGF-I or the recombinant IGF analog [1-27,Gly4,38-70]IGF-I (Analog).	disuccinimidyl	55-69	insulin like growth factor 1	Homo sapiens	82-87	
2174333-6	1990	The bioactive binding protein(s) was cross-linked with disuccinimidyl suberate to IGF-I or the recombinant IGF analog [1-27,Gly4,38-70]IGF-I (Analog).	disuccinimidyl	55-69	insulin like growth factor 1	Homo sapiens	135-140	
1690749-4	1990	When [125I]IGF-I or [125I]IGF-II was cross-linked to the 150K BP with disuccinimidyl suberate and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (10-15%) and autoradiography, four specifically labeled complexes of 20K, 24K, 33K, and 47K mol wt were identified.	disuccinimidyl	70-84	insulin like growth factor 1	Homo sapiens	11-16	
2958982-5	1987	Results from disuccinimidyl suberate cross-linking of 125I-IGF-I to muscle-derived ovine fibroblasts in the presence of related polypeptides verified the competitive binding data.	disuccinimidyl	13-27	insulin like growth factor 1	Homo sapiens	59-64	
2557332-4	1989	Cross-linking of 125I-IGF-I to the cell surface with disuccinimidyl suberate followed by analysis with sodium dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography reveals a 130-kDa protein (reduced) consistent with the alpha component of a type I receptor and a 38-kDa protein which does not bind insulin, and thus could be another IGF-I cell surface binding protein.	disuccinimidyl	53-67	insulin like growth factor 1	Homo sapiens	22-27	
3718510-3	1986	When 125I-IGF-1 was cross-linked to inhibitor using disuccinimidyl suberate, five specifically labelled bands were seen on SDS-PAGE and autoradiography.	disuccinimidyl	52-66	insulin like growth factor 1	Homo sapiens	10-15	
2580858-2	1985	By using disuccinimidyl suberate, we have covalently cross-linked 125I-labeled somatomedin-C (Sm-C)/insulinlike growth factor I to specific binding proteins in human plasma.	disuccinimidyl	9-23	insulin like growth factor 1	Homo sapiens	79-92	
6313160-1	1983	Human placental receptors for insulin and for human basic somatomedin (BSM, analogous to human insulinlike growth factor I (IGF-I] were selectively cross-link labelled with 125I-labelled insulin and BSM using disuccinimidyl suberate under conditions whereby cross-linking of 125I-labelled insulin to the BSM receptor and of 125I-labelled BSM to the insulin receptor was avoided.	disuccinimidyl	209-223	insulin like growth factor 1	Homo sapiens	95-122	
6313160-1	1983	Human placental receptors for insulin and for human basic somatomedin (BSM, analogous to human insulinlike growth factor I (IGF-I] were selectively cross-link labelled with 125I-labelled insulin and BSM using disuccinimidyl suberate under conditions whereby cross-linking of 125I-labelled insulin to the BSM receptor and of 125I-labelled BSM to the insulin receptor was avoided.	disuccinimidyl	209-223	insulin like growth factor 1	Homo sapiens	124-129	
6275879-1	1981	Human placental receptors for insulin and somatomedin C (Sm-C) were affinity labeled with [125I]insulin and [125I]Sm-C by using the bifunctional cross-linking agent disuccinimidyl suberate.	disuccinimidyl	165-179	insulin like growth factor 1	Homo sapiens	42-55