PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24114661-0	2014	Pyrroloquinoline quinone inhibits oxygen/glucose deprivation-induced apoptosis by activating the PI3K/AKT pathway in cardiomyocytes.	PQQ Cofactor	0-24	AKT serine/threonine kinase 1	Rattus norvegicus	102-105	
24114661-8	2014	Western blotting was used to examine the effect of PQQ on the phosphatidylinositol 3-kinase (PI3K)/Akt pathway in the H9C2 cells.	PQQ Cofactor	51-54	AKT serine/threonine kinase 1	Rattus norvegicus	99-102	
24114661-13	2014	Western blot analysis showed that PQQ partially reversed the decrease in Akt phosphorylation that was caused by OGD (p < 0.05).	PQQ Cofactor	34-37	AKT serine/threonine kinase 1	Rattus norvegicus	73-76	
24114661-15	2014	The protective effect of PQQ may be related to its effects on the PI3K/Akt pathway.	PQQ Cofactor	25-28	AKT serine/threonine kinase 1	Rattus norvegicus	71-74	
34733912-16	2021	The expression level of phospho-Akt (p-AKT) increased after SCI and decreased after PQQ treatment.	PQQ Cofactor	84-87	AKT serine/threonine kinase 1	Rattus norvegicus	32-35	
23686346-9	2013	PQQ increased the mRNA and protein expressions of Nrf2, HO-1 and GCLC and the phosphorylation of Akt and GSK3beta in the cortex of glutamate-injected rats.	PQQ Cofactor	0-3	AKT serine/threonine kinase 1	Rattus norvegicus	97-100	
23686346-11	2013	The antioxidant properties of PQQ and PQQ-induced activation of Akt/GSK3beta signal pathway might be responsible for the in vivo neuroprotection of PQQ.	PQQ Cofactor	30-33	AKT serine/threonine kinase 1	Rattus norvegicus	64-67	
23686346-11	2013	The antioxidant properties of PQQ and PQQ-induced activation of Akt/GSK3beta signal pathway might be responsible for the in vivo neuroprotection of PQQ.	PQQ Cofactor	38-41	AKT serine/threonine kinase 1	Rattus norvegicus	64-67	
23686346-11	2013	The antioxidant properties of PQQ and PQQ-induced activation of Akt/GSK3beta signal pathway might be responsible for the in vivo neuroprotection of PQQ.	PQQ Cofactor	38-41	AKT serine/threonine kinase 1	Rattus norvegicus	64-67	
34733912-16	2021	The expression level of phospho-Akt (p-AKT) increased after SCI and decreased after PQQ treatment.	PQQ Cofactor	84-87	AKT serine/threonine kinase 1	Rattus norvegicus	39-42	
35592257-12	2022	Compared with the LPS group, phosphor-protein kinase B (p-Akt)/Akt levels in jejunum and colon were decreased in PQQ treatment groups (P < 0.05).	PQQ Cofactor	113-116	AKT serine/threonine kinase 1	Rattus norvegicus	58-61	
35592257-12	2022	Compared with the LPS group, phosphor-protein kinase B (p-Akt)/Akt levels in jejunum and colon were decreased in PQQ treatment groups (P < 0.05).	PQQ Cofactor	113-116	AKT serine/threonine kinase 1	Rattus norvegicus	63-66	
35592257-14	2022	PQQ-regulated enteric neurochemical plasticity of ENS via the Akt signaling pathway of weaned rats suffering from enteritis.	PQQ Cofactor	0-3	AKT serine/threonine kinase 1	Rattus norvegicus	62-65