PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23686346-9 2013 PQQ increased the mRNA and protein expressions of Nrf2, HO-1 and GCLC and the phosphorylation of Akt and GSK3beta in the cortex of glutamate-injected rats. PQQ Cofactor 0-3 NFE2 like bZIP transcription factor 2 Rattus norvegicus 50-54 34542890-9 2022 A mechanism study showed that PQQ may achieve the above therapeutic effects by inhibiting NF-kappaB and promoting Nrf2 antioxidant pathways. PQQ Cofactor 30-33 NFE2 like bZIP transcription factor 2 Rattus norvegicus 114-118 34542890-10 2022 In conclusion, we showed the protective effect of PQQ on PE-like model rats, by improving anti-inflammation and antioxidation effect through the NF-kappaB-Nrf2 pathway. PQQ Cofactor 50-53 NFE2 like bZIP transcription factor 2 Rattus norvegicus 155-159