PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31647241-7 2019 We have synthesized new azide-terminated coumarin linkers that we react with the amine groups of insulin. Azides 24-29 insulin Homo sapiens 97-104 1311714-1 1992 Insulin caused a transient increase in H2O2 accumulation in human fat cell suspensions that was observed only in the presence of an inhibitor of catalase and heme-containing peroxidases, such as azide, and reached peak levels of 30 microM within 5 min. Azides 195-200 insulin Homo sapiens 0-7 30946565-0 2019 Site-Selective Synthesis of Insulin Azides and Bioconjugates. Azides 36-42 insulin Homo sapiens 28-35 26792393-3 2016 Here, we aimed to stabilize and modulate the receptor-compatible conformation of insulin by covalent intra-chain crosslinking within its B22-B30 segment, using the Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition reaction of azides and alkynes. Azides 226-232 insulin Homo sapiens 81-88 27171861-5 2016 Insulin modified with either one or two light cleavable azide groups is polymerized with a tridentate alkyne-bridging monomer using a click reaction. Azides 56-61 insulin Homo sapiens 0-7