PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11592731-11	2001	In addition, orlistat, the inhibitor of lipase, abolished human BSSL activity against p-nitrophenyl acetate and slightly reduced its activity against ceramide but had no inhibitory effect on ceramidase activity isolated by HQ chromatography.	Orlistat	13-21	carboxyl ester lipase	Homo sapiens	64-68	
3167082-2	1988	In addition to pancreatic lipase, it is shown in the present study that tetrahydrolipstatin also inhibits human gastric lipase, carboxyl ester lipase (cholesterol esterase) of pancreatic origin and the closely related bile-salt-stimulated lipase of human milk.	Orlistat	72-91	carboxyl ester lipase	Homo sapiens	128-149	
3167082-2	1988	In addition to pancreatic lipase, it is shown in the present study that tetrahydrolipstatin also inhibits human gastric lipase, carboxyl ester lipase (cholesterol esterase) of pancreatic origin and the closely related bile-salt-stimulated lipase of human milk.	Orlistat	72-91	carboxyl ester lipase	Homo sapiens	151-171	
3167082-6	1988	In aqueous solution, in the absence of substrate, the inhibition of carboxyl ester lipase by tetrahydrolipstatin has the characteristics of being reversible, and finally becomes of a temporary nature analogues to the trypsin-trypsin inhibitor system.	Orlistat	93-112	carboxyl ester lipase	Homo sapiens	68-89	
30610953-9	2019	Furthermore, we identified orlistat as a potent inhibitor of cholesterol esterase and found it to be an ideal compound for the study of the enzymatic process in vivo.	Orlistat	27-35	carboxyl ester lipase	Homo sapiens	61-81