PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9869661-0 1999 In vivo involvement of cytochrome P450 4A family in the oxidative metabolism of the lipid peroxidation product trans-4-hydroxy-2-nonenal, using PPARalpha-deficient mice. 4-hydroxy-2-nonenal 111-136 peroxisome proliferator activated receptor alpha Mus musculus 144-153 27543085-9 2016 4-Hydroxynonenal-induced reactive oxygen species production, which resulted in LRP6 stability, was suppressed by overexpression of PPARalpha and dramatically enhanced in PPARalpha-/- tubular cells. 4-hydroxy-2-nonenal 0-16 peroxisome proliferator activated receptor alpha Mus musculus 131-140 27543085-9 2016 4-Hydroxynonenal-induced reactive oxygen species production, which resulted in LRP6 stability, was suppressed by overexpression of PPARalpha and dramatically enhanced in PPARalpha-/- tubular cells. 4-hydroxy-2-nonenal 0-16 peroxisome proliferator activated receptor alpha Mus musculus 170-179 22982442-10 2012 Prevention of intracellular 4-HNE accumulation by bezafibrate, a peroxisome proliferator-activated receptor-alpha agonist, protected hepatocytes from TNF killing via NF-kappaB activation. 4-hydroxy-2-nonenal 28-33 peroxisome proliferator activated receptor alpha Mus musculus 65-113