PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18598755-6 2008 Overall, our results suggest that decreased OGG1 activity occurs early in the progression of AD, possibly mediated by 4-hydroxynonenal inactivation and may contribute to elevated 8-OHdG in the brain in MCI and LAD. 4-hydroxy-2-nonenal 118-134 8-oxoguanine DNA glycosylase Homo sapiens 44-48