PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21950100-4	2011	Also revealed is augmentation of lymphocyte caspase-3 functional activity 4 h after generation of singlet oxygen, hydroxyl radical and hydrogen peroxide addition, as well as 8 and 24 and 6 and 8 h after UV-irradiation of the cells at doses 151 and 1510 J/m2, correspondingly.	Hydroxyl Radical	114-130	caspase 3	Homo sapiens	44-53	
11844698-2	2002	Here we demonstrate that hydroxyl radicals generated selectively by photolysis of a photo-Fenton reagent, N,N"-bis(2-hydroperoxy-2-methoxyethyl)-1,4,5,8-naphthaldiimide (NP-III), induce apoptosis in HL-60 (human promyelocytic leukemia) cells involving the activation of caspase-3.	Hydroxyl Radical	25-42	caspase 3	Homo sapiens	270-279	
11163759-5	2001	Moreover, we found that hydroxyl radical-induced apoptosis in telomerase-expressing and control fibroblasts was caspase-3 independent.	Hydroxyl Radical	24-40	caspase 3	Homo sapiens	112-121	
11315194-0	2001	Hydrogen peroxide and hydroxyl radical involvement in the activation of caspase-3 in chemically induced apoptosis of HL-60 cells.	Hydroxyl Radical	22-38	caspase 3	Homo sapiens	72-81	
11315194-3	2001	These results suggest that hydrogen peroxide and the hydroxyl radical are common mediators of caspase-3 activation caused by these chemicals, with apparently different functional mechanisms.	Hydroxyl Radical	53-69	caspase 3	Homo sapiens	94-103