PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12600983-3 2003 To elucidate the molecular mechanisms underlying SREBP-1c-induced beta-cell dysfunction, we employed the Tet-On inducible system to achieve tightly controlled and conditional expression of the nuclear active form of SREBP-1c (naSREBP-1c) in INS-1 cells. tetramethylenedisulfotetramine 105-108 sterol regulatory element binding transcription factor 1 Rattus norvegicus 216-224