PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21870251-2	2011	Since PARP-1 gene is expressed constitutively, its activation cannot be surmised from increased expression of its mRNA or protein, but by demonstrating the consequences of its catalytic -reaction which results in consumption of the substrate nicotinamide adenine dinucleotide (NAD(+)) and formation of three products, namely, polymer of ADP-ribose (pADPr or PAR), nicotinamide, and protons.	Adenosine Diphosphate Ribose	337-347	jumping translocation breakpoint	Homo sapiens	6-9	
32439163-4	2020	Here, we demonstrate that PAR glycohydrolases (PARGs) from mammals to bacteria have a robust endo-glycohydrolase activity, releasing protein-free PAR chains longer than three ADP-ribose units as early reaction products.	Adenosine Diphosphate Ribose	175-185	jumping translocation breakpoint	Homo sapiens	26-29	
32439163-4	2020	Here, we demonstrate that PAR glycohydrolases (PARGs) from mammals to bacteria have a robust endo-glycohydrolase activity, releasing protein-free PAR chains longer than three ADP-ribose units as early reaction products.	Adenosine Diphosphate Ribose	175-185	jumping translocation breakpoint	Homo sapiens	47-50	
32439163-5	2020	Released PAR chains are transient and rapidly degraded to monomeric ADP-ribose, which is consistent with a short half-life of PAR during DNA damage responses.	Adenosine Diphosphate Ribose	68-78	jumping translocation breakpoint	Homo sapiens	9-12	
32439163-5	2020	Released PAR chains are transient and rapidly degraded to monomeric ADP-ribose, which is consistent with a short half-life of PAR during DNA damage responses.	Adenosine Diphosphate Ribose	68-78	jumping translocation breakpoint	Homo sapiens	126-129