PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21414769-9	2012	Kuguacin J also inhibited the incorporation of [125I]-iodoarylazidoprazosin into P-gp in a concentration-dependent manner, indicating that kuguacin J directly interacts with the drug-substrate-binding site on P-gp.	azidoprazosin	47-75	phosphoglycolate phosphatase	Homo sapiens	81-85	
26820614-7	2016	P-gp ATPase assays and photo-cross-linking with [(125)I]iodoarylazidoprazosin confirmed that transport and biochemical properties of P-gp chimeras were similar to those of wild-type P-gp, although differences in drug binding were detected when human and mouse transmembrane domains were combined.	azidoprazosin	56-77	phosphoglycolate phosphatase	Homo sapiens	133-137	
26820614-7	2016	P-gp ATPase assays and photo-cross-linking with [(125)I]iodoarylazidoprazosin confirmed that transport and biochemical properties of P-gp chimeras were similar to those of wild-type P-gp, although differences in drug binding were detected when human and mouse transmembrane domains were combined.	azidoprazosin	56-77	phosphoglycolate phosphatase	Homo sapiens	133-137	
24865254-6	2014	A set of in vitro experiments including kinase activity and cell-based transport assays and photolabeling of P-gp and ABCG2 with a transport substrate, [(125)I]-iodoarylazido-prazosin (IAAP), were carried out in isolated membranes to evaluate the potency of the derivatives to inhibit the function of ABC drug transporters and BCR-ABL kinase.	azidoprazosin	161-183	phosphoglycolate phosphatase	Homo sapiens	109-113	
21414769-9	2012	Kuguacin J also inhibited the incorporation of [125I]-iodoarylazidoprazosin into P-gp in a concentration-dependent manner, indicating that kuguacin J directly interacts with the drug-substrate-binding site on P-gp.	azidoprazosin	47-75	phosphoglycolate phosphatase	Homo sapiens	209-213	
16729976-3	2006	Unlike most other Pgp modulators, the cis isomer of flupentixol [cis-(Z)-flupentixol] facilitates interaction of Pgp with its transport-substrate [125I]iodoarylazidoprazosin (or [125I]IAAP), yet inhibits transport.	azidoprazosin	152-173	phosphoglycolate phosphatase	Homo sapiens	113-116	
16960658-12	2007	THC stimulated P-gp ATPase activity and inhibited the incorporation of [(125)I]-iodoarylazidoprazosin (IAAP) into P-gp in a concentration-dependent manner.	azidoprazosin	71-101	phosphoglycolate phosphatase	Homo sapiens	114-118	
7682843-5	1993	Labeling experiments with the photoactivatable P-gp ligands iodoarylazidoprazosin and azidopine indicate a strong reduction in binding of these photoactivatable probes to the mutant P-gps (1F, 3F) as compared to their wild-type counterparts (1S,3S).	azidoprazosin	60-81	phosphoglycolate phosphatase	Homo sapiens	47-51	
10350482-2	1999	The rate of ATP hydrolysis by Pgp and photoaffinity labeling of Pgp with the substrate analogue [125I]iodoarylazidoprazosin ([125I]IAAP) are modulated by each isomer in an opposite manner, suggesting different mechanisms for the inhibitory effect on drug transport.	azidoprazosin	96-123	phosphoglycolate phosphatase	Homo sapiens	30-33	
10350482-2	1999	The rate of ATP hydrolysis by Pgp and photoaffinity labeling of Pgp with the substrate analogue [125I]iodoarylazidoprazosin ([125I]IAAP) are modulated by each isomer in an opposite manner, suggesting different mechanisms for the inhibitory effect on drug transport.	azidoprazosin	96-123	phosphoglycolate phosphatase	Homo sapiens	64-67	
9530286-4	1998	Furthermore, photoaffinity labeling of P-gp with the substrate analogue [125I]iodoarylazidoprazosin (IAAP) was inhibited by all three inhibitors.	azidoprazosin	72-99	phosphoglycolate phosphatase	Homo sapiens	39-43	
9530286-4	1998	Furthermore, photoaffinity labeling of P-gp with the substrate analogue [125I]iodoarylazidoprazosin (IAAP) was inhibited by all three inhibitors.	azidoprazosin	101-105	phosphoglycolate phosphatase	Homo sapiens	39-43