PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21223996-5 2011 5-HT2A and 5-HT2B receptor agonist-induced pMF were both blocked by selective antagonists (ketanserin and SB206553, respectively), but not by antagonists to the other receptor subtype. SB 206553 106-114 5-hydroxytryptamine receptor 2B Rattus norvegicus 11-17 20980537-10 2011 In contrast, inverse agonists (such as SB206553) that block constitutive activity at 5-HT(2B) or 5-HT(2C) receptors markedly reduced the LLRs, indicating the presence of constitutive activity in these receptors. SB 206553 39-47 5-hydroxytryptamine receptor 2B Rattus norvegicus 85-92 9225307-9 1997 These behavioural profiles suggest that blockade of the 5-HT2A receptor may not reduce anxiety and demonstrate that 5-HT2B and/or 5-HT2C receptor subtypes may be primarily involved in the anxiolytic-like effects of mianserin and SB 206553 in rats. SB 206553 229-238 5-hydroxytryptamine receptor 2B Rattus norvegicus 116-122 16495076-7 2006 SB 206553 (1 mg kg(-1) s.c.), a selective 5-HT2B/2C receptor antagonist, also inhibited the BW 723C86-mediated responses. SB 206553 0-9 5-hydroxytryptamine receptor 2B Rattus norvegicus 42-48