PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2494942-2	1989	A unique regioselectivity difference between cytochromes P450b and P450e for the metabolism of 7,12-dimethylbenz[a]anthracene (DMBA) and a genetic deficiency in P450e expression in the Marshall (M520/N) rat strain have been exploited to determine the microsomal contributions of the respective forms toward the metabolism of DMBA.	anthracene	115-125	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	57-62	
8482321-4	1993	A significant sister chromatid exchange inducing effect was found after a 24 h exposure in each of the genetically engineered cell lines, except for benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in CYP2B1 expressing cells, and for benzo[a]pyrene in cells expressing both CYP1A2 and acetyltransferase.	anthracene	188-198	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	202-208	
1547225-2	1992	CYP2B1 and CYP2B2 cytochromes were equally well expressed (110-140 pmol/mg of microsomal protein) and catalyzed metabolism of 7,12-dimethylbenz[a]anthracene (DMBA).	anthracene	146-156	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	0-6	
3113333-5	1987	Anti P-450b/e inhibited total metabolism of 7,12-dimethylbenz[a]anthracene (DMBA) by uninduced microsomes, to an extent dependent on rat strain (15-30%), predominantly through inhibition of formation of 12-hydroxymethyl-7-methyl BA (12HOMMBA) (65-85%), the major metabolite of purified P-450e.	anthracene	64-74	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	5-13