PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28554847-2	2017	Studies with drugs that interfere with serotonin-mediated neurotransmission suggest that the mu-opioid receptor (MOR) synergistically interacts with the 5-HT1A receptor in the dPAG to inhibit escape, a panic-related behavior.	dpag	176-180	5-hydroxytryptamine receptor 1A	Homo sapiens	153-168	
26320545-1	2015	Previously reported results have shown that the inhibitory effect of fluoxetine on escape behavior, interpreted as a panicolytic-like effect, is blocked by pretreatment with either the opioid receptor antagonist naloxone or the 5-HT1A receptor (5-HT1A-R) antagonist WAY100635 via injection into the dorsal periaqueductal gray matter (dPAG).	dpag	334-338	5-hydroxytryptamine receptor 1A	Homo sapiens	228-243	
28347824-3	2017	The 5-HT1A receptor (5-HT1A-R) is involved in regulating escape behavior that is organized in the dPAG.	dpag	98-102	5-hydroxytryptamine receptor 1A	Homo sapiens	4-19	
28347824-3	2017	The 5-HT1A receptor (5-HT1A-R) is involved in regulating escape behavior that is organized in the dPAG.	dpag	98-102	5-hydroxytryptamine receptor 1A	Homo sapiens	21-29	
28347824-12	2017	These results indicate that KOR enhances proximal defense in the dPAG through 5-HT1A-R modulation, independently of MOR.	dpag	65-69	5-hydroxytryptamine receptor 1A	Homo sapiens	78-86	
26320545-1	2015	Previously reported results have shown that the inhibitory effect of fluoxetine on escape behavior, interpreted as a panicolytic-like effect, is blocked by pretreatment with either the opioid receptor antagonist naloxone or the 5-HT1A receptor (5-HT1A-R) antagonist WAY100635 via injection into the dorsal periaqueductal gray matter (dPAG).	dpag	334-338	5-hydroxytryptamine receptor 1A	Homo sapiens	245-253	
26320545-2	2015	Additionally, reported evidence indicates that the mu-opioid receptor (MOR) interacts with the 5-HT1A-R in the dPAG.	dpag	111-115	5-hydroxytryptamine receptor 1A	Homo sapiens	95-103	
21421022-3	2011	Since reported evidence has implicated the 5-HT(1A) receptors of the dorsal periaqueductal gray matter (DPAG) in the panicolytic effect of antidepressants, rats treated with pindolol (5.0mg/kg, i.p.)	dpag	104-108	5-hydroxytryptamine receptor 1A	Homo sapiens	43-50	
21421022-7	2011	These results implicate the 5-HT(1A) receptors of the DPAG in the panicolytic effect of the pindolol-paroxetine combination administered systemically.	dpag	54-58	5-hydroxytryptamine receptor 1A	Homo sapiens	28-35	
20528764-6	2010	The reviewed results suggest that chronic, but not acute, administration of antidepressants suppress panic attacks by increasing the release of 5-HT and enhancing the responsivity of post-synaptic 5-HT1A and 5-HT2A receptors in the DPAG.	dpag	232-236	5-hydroxytryptamine receptor 1A	Homo sapiens	197-209