PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12522118-5 2003 Therefore, we investigated RLX-induced regulation of ET(B) in human umbilical vein endothelial, epithelial (HeLa), and vascular smooth muscle cells. Relaxin 27-30 endothelin receptor type B Homo sapiens 53-58 12522118-11 2003 RLX pretreatment augmented the dilator effect of the ET(B) agonist endothelin-3 by 100+/-8% and 133+/-13%. Relaxin 0-3 endothelin receptor type B Homo sapiens 53-58 12522118-12 2003 In conclusion, RLX stimulates endothelial and epithelial ET(B) via a Ras-independent Raf-1-MEK-1-ERK-1/2 pathway that activates NF-kappaB. Relaxin 15-18 endothelin receptor type B Homo sapiens 57-62