PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26575826-8	2016	Cell death induced by combined treatment is Noxa- and/or BIM-dependent in some cell lines but in others appears to be mediated by down-regulation of BCL-XL and release of BAK from BCL-XL and MCL-1.	bim	57-60	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	191-196	
26947081-6	2016	Thus, MCL-1 has a major role in lymphoma initiating pro-B cells to oppose BIM, which is upregulated in response to oncogenic stress.	bim	74-77	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	6-11	
17698840-5	2007	In addition, TRAIL caused increased binding of Bim and Puma to Mcl-1 that was inhibited by IETD(OMe)-fmk but not SP600125.	bim	47-50	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	63-68	
17698840-7	2007	Collectively, these observations not only suggest a model in which Mcl-1 confers TRAIL resistance by serving as a buffer for Bak, Bim, and Puma, but also identify sorafenib as a potential modulator of TRAIL sensitivity.	bim	130-133	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	67-72	
17200126-8	2007	Knockdown of Bim and Bak, downstream targets of Mcl-1, inhibited cycloheximide-induced apoptosis, as did knockdown of Bax.	bim	13-16	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	48-53	
15378010-0	2004	Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.	bim	65-68	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	12-17	
17545623-13	2007	Thus, in myeloma cells, the mechanistic basis for bortezomib sensitivity can be explained mainly by the model in which the sensitizer Noxa can displace Bim, a BH3-only activator, from Mcl-1, thus leading to Bax/Bak activation.	bim	152-155	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	184-189