PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28360094-4 2017 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM344) potentiated glutamate-evoked currents of GluK2a 21-fold at the highest concentration tested (200 muM), with an EC50 of 79 muM. Saccharin 61-72 latexin Homo sapiens 180-183 28360094-4 2017 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM344) potentiated glutamate-evoked currents of GluK2a 21-fold at the highest concentration tested (200 muM), with an EC50 of 79 muM. Saccharin 61-72 latexin Homo sapiens 205-208 27721153-3 2017 In vitro studies showed that the majority of saccharin derivatives with piperazine moiety and one phthalimide derivative with 3-aminopiperidine fragment exhibited inhibitory potency toward acetylcholinesterase (AChE) with EeAChE IC50 values ranging from 0.83 muM to 19.18 muM. Saccharin 45-54 latexin Homo sapiens 259-262 27721153-3 2017 In vitro studies showed that the majority of saccharin derivatives with piperazine moiety and one phthalimide derivative with 3-aminopiperidine fragment exhibited inhibitory potency toward acetylcholinesterase (AChE) with EeAChE IC50 values ranging from 0.83 muM to 19.18 muM. Saccharin 45-54 latexin Homo sapiens 272-275