PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35598544-0 2022 Effect of saccharin, a non-nutritive sweeteners, on insulin and blood glucose levels in healthy young men: A crossover trial. Saccharin 10-19 insulin Homo sapiens 52-59 12213059-4 2002 6-Chloro-3-(1-methylcyclobutyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide (54) was found to bind and activate the SUR1/Kir6.2 K(ATP) channels in the low nanomolar range and to be at least 1000 times more potent than the reference compound diazoxide with respect to inhibition of insulin release from rat islets. Saccharin 72-83 insulin Homo sapiens 289-296 12213059-1 2002 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives were synthesized and characterized as activators of adenosine 5"-triphosphate (ATP) sensitive potassium (K(ATP)) channels in the beta-cells by measuring effects on membrane potential and insulin release in vitro. Saccharin 57-68 insulin Homo sapiens 268-275 18556090-7 2008 A significant increase of plasma insulin concentration was apparent after stimulation with sucrose and saccharin. Saccharin 103-112 insulin Homo sapiens 33-40