PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15322260-6 2004 The effects of bupropion and enantiomers of hydroxybupropion on human nAChR subtypes indicate that the (2S,3S) isomer is more potent than the (2S,3R) isomer or racemic bupropion as an antagonist of alpha(4)beta(2) (functional IC(50) = 3.3 microM). Saccharin 103-110 cholinergic receptor nicotinic alpha 4 subunit Homo sapiens 70-75