PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27683267-3 2016 Mouse body weights and testis weights in middle- and low-dose saccharin-treated groups were increased with up-expressions of molecules involved in testicular sweet taste and steroidogenic (middle saccharin: steroidogenic acute regulatory protein [StAR]; P450 cholesterol side-chain cleavage enzyme [CYP11A1]; 17-alpha-hydroxylase/C17,20-lyase [CYP17A1]; low saccharin: StAR). Saccharin 62-71 cytochrome P450, family 17, subfamily a, polypeptide 1 Mus musculus 344-351 27683267-4 2016 Moreover, a high-dose saccharin-related decline in reproductive hormone levels and injuries to testis and sperm were observed to be associated with suppression of testicular T1R3 and Galpha, as well as steroidogenic-related factors (StAR; 3-beta-hydroxysteroid dehydrogenase [3-beta-HSD]; CYP11A1; CYP17A1; 17-beta-hydroxysteroid dehydrogenase [17-beta-HSD]), and activation of cleaved caspase-3. Saccharin 22-31 cytochrome P450, family 17, subfamily a, polypeptide 1 Mus musculus 298-305