PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18573750-5 2008 Evaluation of biomarkers of lead exposure and/or effect revealed alarming blood lead levels [(3.92+/-0.94) micromol L-1], 50 % reduction in the activity of delta-aminolevulinic acid dehydratase [(24.67+/-5.12) U L-1] and an increase in zinc protoporphyrin [(1228+/-480) microg L-1]. zinc protoporphyrin 236-255 aminolevulinate dehydratase Homo sapiens 156-193 26653370-11 2015 ZPP level was negatively correlated with ALAD concentration (r=-0. zinc protoporphyrin 0-3 aminolevulinate dehydratase Homo sapiens 41-45 26653370-17 2015 The workers with ALAD1-2 genotype had a significantly lower ALAD activity, and a significantly higher ZPP level compared with those ALAD1-1 genotype (P<0.01). zinc protoporphyrin 102-105 aminolevulinate dehydratase Homo sapiens 17-21 24631795-6 2014 The urine ALA and blood ZPP levels in workers with the ALAD 1-1 genotype were higher than those with the ALADl-2 genotype. zinc protoporphyrin 24-27 aminolevulinate dehydratase Homo sapiens 55-59 15915653-5 2005 Exposure and effect biomarkers were significantly each other correlated among ALAD-1-1 subjects only, who showed also a significant inverse relationship between ALAD activity and ZPP values. zinc protoporphyrin 179-182 aminolevulinate dehydratase Homo sapiens 78-82 20021040-0 2006 Delta-aminolevulinic Acid dehydratase genotype and its relationship with blood lead and zinc protoporphyrin levels in lead-exposed children living in a smelter community in northern Mexico. zinc protoporphyrin 88-107 aminolevulinate dehydratase Homo sapiens 0-37 20021040-2 2006 Therefore, our purpose was to evaluate the distribution of ALAD genotype and its association with biomarkers of exposure (PbB levels) and effect (Blood ZPP) among children living in a smelter community in Mexico. zinc protoporphyrin 152-155 aminolevulinate dehydratase Homo sapiens 59-63 20021040-11 2006 A significant increase in the odds ratio (OR) for the effect of lead exposure on ZPP levels was observed for ALAD (1-1) children having PbB values above 20 mu g/dL, as compared to those having PbB levels below 10 mu g/dL (OR = 2.95, 95% CI = 1.45-5.97; p = 0.003), whereas no significant increases were observed for the ALAD (1-2/2-2) children. zinc protoporphyrin 81-84 aminolevulinate dehydratase Homo sapiens 109-113 20021040-11 2006 A significant increase in the odds ratio (OR) for the effect of lead exposure on ZPP levels was observed for ALAD (1-1) children having PbB values above 20 mu g/dL, as compared to those having PbB levels below 10 mu g/dL (OR = 2.95, 95% CI = 1.45-5.97; p = 0.003), whereas no significant increases were observed for the ALAD (1-2/2-2) children. zinc protoporphyrin 81-84 aminolevulinate dehydratase Homo sapiens 320-324 15915653-5 2005 Exposure and effect biomarkers were significantly each other correlated among ALAD-1-1 subjects only, who showed also a significant inverse relationship between ALAD activity and ZPP values. zinc protoporphyrin 179-182 aminolevulinate dehydratase Homo sapiens 161-165 15064157-1 2004 Previous studies have suggested that delta-aminolevulinic acid dehydratase (ALAD) types 1-2 or 2-2 are protective against the toxicity of blood lead (PbB) when zinc protoporphyrin (ZPP) levels are low because of differential binding of lead in erythrocytes. zinc protoporphyrin 160-179 aminolevulinate dehydratase Homo sapiens 37-74 15064157-1 2004 Previous studies have suggested that delta-aminolevulinic acid dehydratase (ALAD) types 1-2 or 2-2 are protective against the toxicity of blood lead (PbB) when zinc protoporphyrin (ZPP) levels are low because of differential binding of lead in erythrocytes. zinc protoporphyrin 160-179 aminolevulinate dehydratase Homo sapiens 76-80 15064157-1 2004 Previous studies have suggested that delta-aminolevulinic acid dehydratase (ALAD) types 1-2 or 2-2 are protective against the toxicity of blood lead (PbB) when zinc protoporphyrin (ZPP) levels are low because of differential binding of lead in erythrocytes. zinc protoporphyrin 181-184 aminolevulinate dehydratase Homo sapiens 37-74 15064157-1 2004 Previous studies have suggested that delta-aminolevulinic acid dehydratase (ALAD) types 1-2 or 2-2 are protective against the toxicity of blood lead (PbB) when zinc protoporphyrin (ZPP) levels are low because of differential binding of lead in erythrocytes. zinc protoporphyrin 181-184 aminolevulinate dehydratase Homo sapiens 76-80 12411083-6 2002 CONCLUSIONS: It was suggested that the ALAD gene polymorphism modified the relationship between blood lead and ZPP and the VDR gene variants influenced the skull development in children living under lead-polluted environment. zinc protoporphyrin 111-114 aminolevulinate dehydratase Homo sapiens 39-43 11413692-0 2001 [Relationship between delta-aminolevulinic acid dehydratase gene polymorphism and blood levels of lead and zinc protoporphyrin in children exposed to lead]. zinc protoporphyrin 107-126 aminolevulinate dehydratase Homo sapiens 22-59 11413692-1 2001 OBJECTIVE: To explore the associations of polymorphism of delta-aminolevulinic acid dehydratase (ALAD) gene with blood levels of lead and zinc protoporphyrin (ZPP). zinc protoporphyrin 159-162 aminolevulinate dehydratase Homo sapiens 97-101 11413692-1 2001 OBJECTIVE: To explore the associations of polymorphism of delta-aminolevulinic acid dehydratase (ALAD) gene with blood levels of lead and zinc protoporphyrin (ZPP). zinc protoporphyrin 138-157 aminolevulinate dehydratase Homo sapiens 58-95 11413692-1 2001 OBJECTIVE: To explore the associations of polymorphism of delta-aminolevulinic acid dehydratase (ALAD) gene with blood levels of lead and zinc protoporphyrin (ZPP). zinc protoporphyrin 138-157 aminolevulinate dehydratase Homo sapiens 97-101 11413692-1 2001 OBJECTIVE: To explore the associations of polymorphism of delta-aminolevulinic acid dehydratase (ALAD) gene with blood levels of lead and zinc protoporphyrin (ZPP). zinc protoporphyrin 159-162 aminolevulinate dehydratase Homo sapiens 58-95 9495797-9 1998 The ALAD genetic polymorphism appears to modify the association between blood lead concentration and ZPP. zinc protoporphyrin 101-104 aminolevulinate dehydratase Homo sapiens 4-8 7572945-0 1995 Associations of delta-aminolevulinic acid dehydratase genotype with plant, exposure duration, and blood lead and zinc protoporphyrin levels in Korean lead workers. zinc protoporphyrin 113-132 aminolevulinate dehydratase Homo sapiens 16-53