PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32657424-8 2021 Furthermore, we found that blocked the Nrf2/HO-1 signaling by the HO-1 inhibitor zinc protoporphyrin IX (Znpp) significantly retrieved H9c2 cells apoptosis that inhibited by GRP78 overexpression. zinc protoporphyrin 81-103 NFE2 like bZIP transcription factor 2 Rattus norvegicus 39-43 32657424-8 2021 Furthermore, we found that blocked the Nrf2/HO-1 signaling by the HO-1 inhibitor zinc protoporphyrin IX (Znpp) significantly retrieved H9c2 cells apoptosis that inhibited by GRP78 overexpression. zinc protoporphyrin 105-109 NFE2 like bZIP transcription factor 2 Rattus norvegicus 39-43 29642608-5 2018 Nrf2 siRNA or HO-1 inhibitor zinc protoporphyrin (ZnPP) reduced the neuroprotective effect. zinc protoporphyrin 50-54 NFE2 like bZIP transcription factor 2 Rattus norvegicus 0-4 32621855-3 2020 The aim of this work was to study the possible protective effect of TDF against CIS-induced testicular toxicity in rats and the possible involvement of Nrf2/HO-1 pathway, which demonstrates antioxidant and inflammatory activities utilizing zinc protoporphyrin-IX (ZnPP) as HO-1 inhibitor. zinc protoporphyrin 240-262 NFE2 like bZIP transcription factor 2 Rattus norvegicus 152-156 32621855-3 2020 The aim of this work was to study the possible protective effect of TDF against CIS-induced testicular toxicity in rats and the possible involvement of Nrf2/HO-1 pathway, which demonstrates antioxidant and inflammatory activities utilizing zinc protoporphyrin-IX (ZnPP) as HO-1 inhibitor. zinc protoporphyrin 264-268 NFE2 like bZIP transcription factor 2 Rattus norvegicus 152-156 30010455-10 2019 Furthermore, FA treatment strengthened intestinal barrier function via increasing the phosphorylation levels of Akt, nuclear factor-erythroid 2-related factor 2 (Nrf2) and hemeoxygenase-1 (HO-1) protein expression, which was reversed by zinc protoporphyrin (an HO-1 inhibitor). zinc protoporphyrin 237-256 NFE2 like bZIP transcription factor 2 Rattus norvegicus 117-160 32838965-11 2020 To verify whether HO-1 induced by Nrf2 is involved in the resistance to oxidative stress, after the rat RIRI and before inhaling NBHO, we intraperitoneally injected HO-1 specific inhibitor zinc protoporphyrin (ZnPP) (45 mumol/Kg). zinc protoporphyrin 189-208 NFE2 like bZIP transcription factor 2 Rattus norvegicus 34-38 30753968-8 2019 Intriguingly, when we inhibited the Nrf2/HO-1 pathway with the HO-1 inhibitor zinc protoporphyrin IX (ZnPPIX), Nrf2 expression was further increased, but the inhibitory effects of BML-111 on the NF-kappaB pathway and on the subsequent inflammatory response, and the proapoptotic actions on neutrophil were reversed. zinc protoporphyrin 78-100 NFE2 like bZIP transcription factor 2 Rattus norvegicus 36-40 30753968-8 2019 Intriguingly, when we inhibited the Nrf2/HO-1 pathway with the HO-1 inhibitor zinc protoporphyrin IX (ZnPPIX), Nrf2 expression was further increased, but the inhibitory effects of BML-111 on the NF-kappaB pathway and on the subsequent inflammatory response, and the proapoptotic actions on neutrophil were reversed. zinc protoporphyrin 78-100 NFE2 like bZIP transcription factor 2 Rattus norvegicus 111-115 30753968-8 2019 Intriguingly, when we inhibited the Nrf2/HO-1 pathway with the HO-1 inhibitor zinc protoporphyrin IX (ZnPPIX), Nrf2 expression was further increased, but the inhibitory effects of BML-111 on the NF-kappaB pathway and on the subsequent inflammatory response, and the proapoptotic actions on neutrophil were reversed. zinc protoporphyrin 102-108 NFE2 like bZIP transcription factor 2 Rattus norvegicus 36-40 30753968-8 2019 Intriguingly, when we inhibited the Nrf2/HO-1 pathway with the HO-1 inhibitor zinc protoporphyrin IX (ZnPPIX), Nrf2 expression was further increased, but the inhibitory effects of BML-111 on the NF-kappaB pathway and on the subsequent inflammatory response, and the proapoptotic actions on neutrophil were reversed. zinc protoporphyrin 102-108 NFE2 like bZIP transcription factor 2 Rattus norvegicus 111-115 29161661-6 2018 Nrf2 small interfering RNA (siRNA) and the HO-1 inhibitor zinc protoporphyrin (ZnPPIX) significantly increased the nuclear translocation of NF-kB and the production of pro-inflammatory cytokines in HBZY-1 cells. zinc protoporphyrin 79-85 NFE2 like bZIP transcription factor 2 Rattus norvegicus 0-4 23704825-8 2013 The ZnPP group showed lower expression of HO-1 and Nrf2 and lower COHb. zinc protoporphyrin 4-8 NFE2 like bZIP transcription factor 2 Rattus norvegicus 51-55 23904790-10 2013 Finally, transfection of CMECs with the Nrf2 over-expressing lentiviral vector upregulated HO-1 expression with a concomitant increase in cell migration and vascular tube formation induced by hypoxia, and this effect was greatly attenuated in the presence of ZnPP (a HO-1 inhibitor). zinc protoporphyrin 259-263 NFE2 like bZIP transcription factor 2 Rattus norvegicus 40-44